The collapse didn’t happen, thanks to, depending on what you believe, the hundreds of millions of dollars spent upgrading code in the late 90s (whoops, 1990s) or because there was never any real risk of calamity.

But the hype — some would say hysteria — that gripped many as January 1, 2000, was approaching forced the world to consider what would happen if our information networks shut down. Now, imagine if those information networks were inside your body instead.

Your nervous system is kind of like a miniature version of the internet. Your bodily tissue (or fascia) contains approximately 250 million nerve endings, all of which are continuously gathering and sharing electrical impulses back and forth between your brain and the rest of your body. When everything works well, you can just go about your day without giving your nerves a second thought.

But when even a few of those quarter billion nerve endings are damaged or otherwise dysfunctional, you may experience a cascade of calamities throughout your body. Damaged nerves can’t deliver electrical signals optimally, or in some cases at all. This dysfunction can cause pain and a number of other symptoms, including the sensation of pins and needles, muscle problems, and even loss of normal bodily functions like digestion and breathing.

The word for this kind of nerve damage is neuropathy.

Many neurologists recommend surgery or medications as first-line treatments for neuropathy, and in fact, many advanced cases can benefit from this approach. But there’s evidence that some neuropathies, especially in their early stages, could benefit more from what’s in your pantry than what’s in your medicine cabinet.

In this article, we’ll look at neuropathy nutrition and the relationship between what we eat and nerve health.

What Is Neuropathy?

Neuropathy is the medical term for damage to nerves outside of the brain and spinal cord. This damage can cause pain, numbness, weakness, and other uncomfortable and sometimes dangerous symptoms. It’s also called peripheral neuropathy, as it disproportionately affects nerve endings that are located closer to the body’s extremities than the core.

Neuropathy can mess up nerve signals in three ways. It can lead to complete loss of signaling, inappropriate signaling, or distortion of the messages that are sent.

If only one nerve is affected, that’s called mononeuropathy. A common mononeuropathy is carpal tunnel syndrome, which is often caused by repetitive use damage to the median nerve of the arm. Polyneuropathy, which involves multiple nerves (and not talking parrots), is the more common condition.

Types of Neuropathy

There are also subcategories of neuropathy, named for the nerve function they affect.

Motor Neuropathy

Motor neuropathy interferes with the movement of the muscles typically under conscious control, such as those used for walking, grasping things, or talking. Examples include muscle weakness or shrinking, or uncontrollable muscle twitching (which is also called fasciculation).

Sensory Neuropathy

Sensory neuropathy interferes with the transmission of sensory data from the extremities to the brain, such as temperature, the pain from a paper cut (ouch!), the feeling of a light touch, or information about the location of limbs in relation to one another. This can lead to loss of reflexes, coordination, or balance; burns or infections because there’s no impulse to pull away from a hot stove or clean a wound; and feeling pain from stimuli that aren’t actually harmful, such as the weight of a blanket on the feet.

Autonomic Neuropathy

Autonomic neuropathy impairs the brain’s ability to regulate activities that people do not control consciously, such as breathing, digesting food, and heart and gland functions. People who suffer from this type of neuropathy can experience heat intolerance and excessive sweating, light-headedness from low blood pressure, and vision problems, among other things.

Proximal Neuropathy

Proximal neuropathy is a type of nerve damage centered in the hip, buttock, or thigh. It usually causes pain in just one side of the body.

Focal Nerve Neuropathy

Focal nerve neuropathy affects a single nerve and may cause symptoms such as double vision, weakness on one side of the body, or partial paralysis, and associated pain. This type most often targets nerve endings in the legs, hands, head, or torso.

What Causes Neuropathy?

There are more than 100 different conditions, both inherited and developed, that can lead to neuropathy. But a few of them cause the vast majority of cases.

Neuropathy and Diabetes

Diabetes, both types 1  and 2, commonly causes neuropathy. That’s because high glucose levels can damage the small blood vessels that supply your nerves. As those nerves cannot access the nutrients they need, their fibers suffer damage and they may eventually die. At this writing, there’s no known way to reverse the damage once the nerves have atrophied. But there are many ways to prevent and reverse prediabetes and type 2 diabetes. (I hosted a whole masterclass on the topic with diabetes expert Brenda Davis, RD — to watch it for free click here.)

Neuropathy and Autoimmune Diseases

Autoimmune diseases cause harm by attacking the body’s own cells and tissues as if they belonged to a foreign invader. Two autoimmune conditions that target the nerves include Guillain-Barré syndrome and celiac disease.

Guillain-Barré syndrome typically presents after a gastrointestinal or respiratory infection, or following a vaccination. For some reason, the immune system responds to these challenges by starting to destroy the myelin sheath that surrounds the axons of many nerve cells. It can then progress to damaging the axons themselves.

Most people recover fully, a process that can last from a few weeks to a few years. But in some cases, the neuropathy progresses to paralysis that can threaten the ability to breathe.

The most common form of neuropathy that accompanies celiac disease involves both motor and sensory nerves. Other autoimmune diseases, including autoimmune thyroid disease, rheumatoid arthritis, systemic lupus erythematosus, and Sjögren’s syndrome, are linked to both neuropathy and celiac disease. Because the nerve damage appears to be triggered by exposure to gluten, symptoms may improve or even resolve on a gluten-free diet.

Neuropathy and Alcoholism

Neuropathy is among the most common negative side effects of chronic alcohol overconsumption. It typically shows up as pain, pins and needles, and lack of muscle control in the lower extremities. Alcohol, it turns out, directly poisons nerves. And the poor nutrition that often accompanies alcoholism is a separate risk factor for neuropathy. Patients who abuse alcohol also tend to consume fewer other calories, and their gastrointestinal tracts struggle to absorb the nutrients they do encounter.

Because alcoholism is a chronic condition, the neuropathy it causes may become permanent. But in cases that are caught early enough, stopping alcohol consumption may help improve neuropathy.

Other Causes of Neuropathy

Toxins other than alcohol can also cause neuropathy, among them mercury, certain types of toxic mold, and chemotherapy drugs. Injury and trauma can also induce neuropathy if it involves compression or crushing of a nerve, as can happen in automobile accidents, falls, sports, and even some medical procedures.

What Vitamins and Minerals Help with Neuropathy?

We know that certain vitamins and minerals are essential for healthy nerve function. And a lot of studies have looked at specific nutrients focused on supplemental forms and doses, but very few have looked at the impact of dietary nutrients on neuropathy. So it makes sense that one of the best ways to reduce your odds of developing neuropathy is to eat a diet rich in the nutrients known to nourish your nerves. But unfortunately, the evidence for this statement is a bit indirect and circumstantial. Therefore, let’s look at the specific nutrients that have been studied, remembering that all of these nutrients are available in foods as well as in supplements.

Vitamin B12

Vitamin B12 helps your body produce a substance called myelin that shields some nerves and helps them transmit information and sensations faster and more efficiently. You can think of them as the insulation on electrical cables and wires. Getting enough B12 is essential for your health, and specifically for the prevention of neuropathy, which is the most common symptom of B12 deficiency.

Supplementing with B12 (especially in plant-based eaters who have a harder time getting this nutrient from food) can improve peripheral neuropathy, including the forms that are primarily caused by diabetes.

For more on B12, including how to ensure that you’re getting enough along with the best plant-based sources, check out our comprehensive article: Vitamin B12: Why it’s Important and How to Avoid B12 Deficiency.

Vitamin B1

Vitamin B1, also known as thiamine, is also a critical nutrient for your nerves. Peripheral neuropathy can be caused by a B1 deficiency, something that’s seen as part of the cluster of symptoms associated with beriberi. That’s because B1 plays a key role as a coenzyme in carbohydrate metabolism, which is the main energy supply for nerve fibers. It also protects nerves from oxidative damage.

Supplementing (with food-based thiamine or with a synthetic analogue, benfotiamine) or eating foods rich in B1 can help prevent or treat deficiency and neuropathy. In severe cases, patients may need intravenous thiamine to relieve symptoms.

Vitamin B3

Another neurological superhero from the B-Vitamin Cinematic Universe is vitamin B3, aka niacin. B3 plays a key role in the development and survival of nerve cells. Studies of rats have shown that supplementation with this family of vitamins can protect against nerve pain and injury, preserve muscle function and vision, and lessen pain and discomfort. (Our view on the use of animals in medical research is here.)

For people who are dealing with ongoing neuropathy, B3 supplementation appears to help only when done in combination with other B vitamins. When neuropathy is associated with cardiovascular disease, there’s research indicating that B3 may work better in conjunction with statins.

For more on the B vitamin family, check out our article: What B Vitamins Do You Need — And What Are The Best Vegan Sources of B Vitamins?

Vitamin E

Your central and peripheral nervous systems are both big fans (and avid users) of vitamin E. Deficiency of this nutrient negatively affects both systems and can lead to peripheral neuropathy. That’s because not having enough vitamin E can cause changes in peripheral nerves and hasten the loss of a type of neuron known as a DRG cell. DRG — dorsal root ganglia — cells are of particular importance because they are afferent neurons, conveying information inward from the body to the brain and spinal cord.

A 2014 study found that vitamin E supplementation reduced neuropathic pain in patients with diabetes. And a 2021 study of people with peripheral neuropathy caused by chemotherapy also found that vitamin E supplementation was an effective treatment.

For more on vitamin E, including its health benefits and some possible risks of supplementation (spoiler alert: it’s probably better to get it from food than from pills!), read our article on Vitamin E Benefits: Why it Matters & the Best Places to Find It.

Magnesium

Magnesium is important for the nerves to transmit messages optimally, as well as for neuromuscular coordination. Magnesium plays a bunch of roles in the nervous system, including keeping overexcited nerve cells from self-destructing. In blocking a nerve receptor called N-methyl-d-aspartate (NMDA), magnesium both calms the nervous system and prevents pain hypersensitivity.

Patients with diabetic neuropathy also tend to have lower levels of magnesium in their blood. And a 2015 study of rats showed improved neurological function recovery and enhanced nerve regeneration with a high-magnesium diet.

Find out more about magnesium in our article: All About Magnesium: Health Benefits, Risks, & Magnesium-Rich Foods You Should Know About.

Omega-3s

Omega-3s are another nutrient group that’s essential for the development and maintenance of healthy nerves. They can help prevent the death of nerve cells and improve their function by chilling out pro-inflammatory and oxidative stress pathways.

A 2017 study that gave supplements of the omega-3 fatty acids EPA and DHA to mice showed that the supplementation sped up their nerve regeneration and, based on observations of a reduction of pain behaviors, reduced their pain as well.

A 2021 study of humans with diabetic neuropathy also found that the lower the plasma DHA levels, the more prevalent multiple neuropathies were. Giving the subjects omega-3 therapy led to greater nerve regeneration.

Find out more about omega-3s in our comprehensive article: Omega-3s: Why Are They Important — And What Are the Best Sources for Your Health?

Alpha-Lipoic Acid

Alpha-lipoic acid is an antioxidant that your body manufactures in the mitochondria (or energy center) of your cells. It works to eliminate reactive oxygen species (ROS), and helps with neuropathy by improving circulation and enhancing the dilation of blood vessels. It also helps suppress a cytokine called prostaglandin E2, which is a key compound involved in inflammation. By affecting several different pathways of oxidative stress, alpha-lipoic acid may reduce sensory neuropathy pain.

Foods That May Help with Neuropathy

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What to Avoid with Neuropathy

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Recipes That May Help with Neuropathy

Increasing consumption of healing plant-based foods could be a wonderful and gentle support to anyone who is suffering from (or wants to avoid) nerve pain. With these tasty plant-based recipes, incorporating foods that contain supportive nutrients necessary for your nervous system can be enjoyable, simple, and nourishing for your nerves and your entire body.

1. Matcha Muffins

Whether enjoyed with your morning tea or as an afternoon pick-me-up, our Matcha Muffins are a testament to the idea that wholesome ingredients can be both delicious and supportive of your well-being. Made with oats, which contain a type of soluble fiber called beta-glucans, these muffins may aid in reducing inflammation and supporting overall nerve health. Their subtle sweetness and earthy undertones create a harmonious flavor blend that will satisfy your sweet cravings without the refined sugar.

2. Kale Caesar with Tofu Croutons

Kale Caesar with Tofu Croutons has many vital nutrients that can positively influence the health of your nerves. Kale contains sulforaphane, which may go a long way in reducing oxidative stress and inflammation, providing relief to those experiencing nerve damage and discomfort. The creamy Caesar dressing, nutty walnut parmesan, and crunchy tofu croutons are also brimming with nutrients such as B12, omega-3s, and magnesium — all essential for proper nerve functioning. This wholesome salad is a great go-to meal when you are looking for something consistent to enjoy in your journey toward improved nerve health.

3. Saffron Cauliflower and Chickpeas

Saffron may not be the first thing you think of when you consider natural remedies to help with pain relief, but it has actually been shown to have therapeutic effects for those living with neuropathy thanks to its anti-inflammatory properties. When combined with sulforaphane-rich cauliflower, this wholesome side dish will not only be a savory delight for you to enjoy but a nourishing experience for your nervous system as well.

Consider Your Diet When Dealing with Neuropathy

Healthy nerves require good nutrition. And without some specific nutrients, neuropathy can develop or become worse. For people with diabetes, it’s particularly important to eat a diet rich in nutrients, like fruits, vegetables, and whole grains, all of which contain compounds that act like superheroes for our nerves.

On the other hand, some foods, especially those high in sugar and saturated fats, act a bit like neuropathy villains, worsening the problem and causing additional suffering. Once you understand the connection between what’s on your plate and how your nerves feel and function, you can make choices to support your health and quality of life.

Tell us in the comments:

• Have you or anyone you love ever experienced neuropathy?
• What are your favorite foods for neuropathy?
• Which neuropathy-busting recipe will you try next?

Featured Image: iStock.com/Sorapop

Read Next:

• The Best Foods (and Diet) to Help You Tackle Type 2 Diabetes
• How Diet and Good Gut Health Can Help Manage Pain & Inflammation in Rheumatoid Arthritis

The post Neuropathy and Diet: How Nutrition Impacts Nerve Damage appeared first on Food Revolution Network.

The doctrine of signatures says that plants that resemble a condition or body part can in some way treat or alleviate related illnesses. Following that thinking, walnuts, which look like brains, were thought to ease headaches and mental health issues. Similarly, the scarlet roots of bloodroot were thought to treat diseases of the circulatory system. And since ginseng root looks like a human being, it was thought to aid and strengthen all parts of the human body. Indeed, the very word “ginseng” comes from the Chinese word for “man-root.”

But the doctrine of signatures is controversial and based on theory over scientific fact. So is it true that walnuts are actually good for brain health? What other walnut health benefits are there? And are walnuts good for the environment?

What Are Walnuts?

If you’re a word lover, you might enjoy adding “juglandaceous” to your vocabulary, in case you were missing a word for “of or pertaining to walnuts.” Walnuts are proud members of the Juglans genus, along with about 20 other tree species, including hickories and pecans.

Technically, walnuts can be classified as nuts or dry drupes, which is science’s alliterative way of talking about fruits with a single seed and a dry husk. Walnuts grow in groups of two or three and range between 1.5 and 2 inches in circumference.

The nut of the walnut forms inside a soft green outer husk and a hard shell. Crack that shell open carefully enough, and you’ll behold a whole walnut that resembles a human brain — including wrinkles, folds, and ridges.

Types of Walnuts

There are two main types of walnuts that you’re likely to encounter in your culinary adventures: English walnuts (also known as Persian), and black walnuts.

English or Persian Walnuts

English walnuts are the kind most walnut-eaters are familiar with, as they’re the type you’re likely to see in grocery stores. They have a sweet, mild flavor, and feature prominently in desserts, salads, and many savory dishes.

Although Persian walnuts originated in what is now Iran, they’re often referred to as English walnuts because they were brought to England by the Romans and traded throughout Europe. Since then, their popularity has led to them being grown commercially worldwide.

In the US, English walnut trees grow best in USDA Zones 4–8 (a classification system that tells farmers and gardeners which plants are hardy enough to thrive in various locations). More than 99% of US commercially grown English walnuts come from California, which supplies about half of the world’s walnut trade. Romania has become the main producer and exporter of walnuts in Europe.

Black Walnuts

Black walnuts are native to North America, and almost all of them come from trees growing in the wild rather than in commercial orchards. Since black walnut trees don’t grow in neat, evenly-spaced rows, they’re harvested by hand rather than by machine. The largest black walnut processor is Hammons Black Walnuts in Missouri.

Black walnuts are bolder and sweeter than English walnuts, with a distinctive earthy or musky flavor.

These nuts were and are an important part of Indigenous diets in the regions where they grow. It takes a lot of effort to harvest and remove their tough green husks and then crack open their extremely hard, black-ridged shells. There are even specialty nutcrackers made just for black walnuts.

In addition to eating black walnuts, you can use them for their oil, and for making deep black or brown dyes.

Walnut Nutrition

Like other tree nuts, walnuts have been an important source of plant-based fat and protein throughout much of recorded human history. They contain polyunsaturated fat in the form of omega-3 and omega-6 fatty acids, including roughly 2.5 grams per ounce of alpha-linolenic acid (ALA). Omega-3s can also reduce the risk of heart disease and contribute to brain and immune health, as well as bringing anti-inflammatory benefits to the body.

Walnuts are high in B vitamins and are a rich source of minerals, including magnesium, phosphorus, manganese, and copper. Of all the tree nuts, walnuts are antioxidant champs, with higher concentrations than any other commonly consumed tree nut. As a whole plant food, they’re also a solid source of fiber.

Black walnuts may pack an even more potent nutritional punch. They’re higher in zinc and selenium than English walnuts and contain more antioxidants and polyunsaturated fatty acids.

The Health Benefits of Walnuts

Measuring the amounts of nutrients found in walnuts is all well and good, but what’s the effect of all that nutritional goodness on human health? There’s some powerful evidence showing that eating walnuts can benefit your heart, digestive system, and, yes, your brain. They may also be able to fight cancer and decrease chronic inflammation.

Walnuts and Heart Health

A 2013 clinical trial found that people who added walnuts to their diet improved the health of their blood vessels. The addition also improved their cholesterol efflux, a process by which the body removes excess cholesterol from blood vessels. Both of these outcomes are beneficial for heart health.

A large study published in 2018 looked at health and dietary outcomes for over 200,000 participants, none of whom had heart disease at the start of the study. After following them for 25 years, about 14,000 of the participants experienced coronary events (heart attacks and strokes). But those who ate at least one serving of walnuts per week had a 13–26% lower risk of heart disease.

Since walnuts are high in calories, some people worry that they might contribute to weight gain and thus increase the risk of heart disease. A 2018 meta-analysis addressed that very concern.

Researchers looked at 26 studies that included over 1,000 participants, to see the effect that walnuts had on lipid levels, weight, and other heart disease risk factors. Their analysis showed that, on average, walnuts actually lowered total and LDL (“bad”) cholesterol, and didn’t impact weight one way or the other.

Walnuts and Digestion

Walnuts can help to improve your gut health by promoting the growth of beneficial bacteria.

A 2018 study found that when healthy people started eating just 43 grams of walnuts a day, after eight weeks, their gut microbiomes became healthier and more diverse.

Another 2018 study found that eating walnuts increased concentrations of beneficial bacteria that produce a substance called butyrate, which is good for intestinal health. Additionally, walnuts can reduce the number of harmful substances produced by certain bacteria that can cause inflammation and increase “bad” LDL cholesterol.

Walnuts and Brain Health

Now we get to the brain. Are walnuts good for cognitive health?

A 2014 review article concluded that walnuts should be included in prevention strategies against the epidemic of cognitive decline and dementia. The phytochemical substances present in walnuts not only decrease oxidative stress and inflammation in brain cells but also boost communication between neurons, stimulate the formation of new neurons, and assist in the removal of harmful proteins associated with the development of dementia.

While human studies have repeatedly shown that diets that include walnuts are associated with improved cognitive performance and better memory, a 2020 mouse study explored the possible mechanisms for this. The study found that walnuts’ antioxidant and anti-inflammatory properties suppressed the production of free radicals and enhanced antioxidant protection, consequently lowering the risk of brain degeneration. (Our view on the use of animals in medical research is here.)

A 2022 article also reviewed some of the ways walnuts are known to combat neuroinflammation, a major contributor both to aging in general and to neurodegenerative diseases like Alzheimer’s in particular. It quickly got technical on me, with phrases such as “inhibition of peripheral inflammation mediated by macrophages.” But the bottom line is that walnuts appear to reduce neuroinflammation through a number of synergistic biochemical mechanisms.

Walnuts and Cancer

A 2019 clinical trial studied the impact of walnut consumption on breast cancer growth and survival. Women with confirmed breast cancer cases were divided into two groups, one whose members began eating two ounces of walnuts daily after their initial biopsy, and a control group that did not change their diet.

After about two weeks, further samples were taken from the tumors. In the walnut-consuming group, the expression of 456 specific genes in the tumor was significantly altered to encourage cancer cell death and suppress cell growth and migration processes. This supports the idea that eating walnuts could potentially slow the growth of cancer cells and increase breast cancer survival rates.

A 2020 study found that black walnuts also demonstrate impressive anticancer activity, thanks to compounds such as penta-O-galloyl-β-d-glucose and quercetin 3-β-d-glucoside. I tried to remember the names of these compounds by putting them to the tune of “Supercalifragilisticexpialidocious,” but I couldn’t get the syllables to match.

Walnuts and Inflammation

Black walnuts, in particular, show amazing anti-inflammatory powers. Two cultivars, named Surprise and Sparrow, demonstrated the ability to suppress inflammatory human white blood cells in a 2019 test-tube study.

But common English walnuts are no slouches in the anti-inflammatory department, either. In 2020, researchers published the results of a two-year trial in which one group of older adults consumed roughly 15% of their daily calories from walnuts, while others ate a similar but walnut-free diet. They found that the walnuts had a health-promoting effect on several inflammatory molecules implicated in cardiovascular disease.

Walnuts may battle inflammation through a compound known as ellagitannins, which can do some very cool anti-inflammatory things. It breaks down in your body to release another compound called ellagic acid. And your gut bacteria then transform this into substances called urolithins, which may have strong anti-inflammatory properties.

Are Walnuts Sustainable?

In general, nuts and other plant-based protein sources produce far fewer greenhouse gas emissions than animal-based food products. The main issue for walnuts is their need for water since half the English walnuts consumed in the world are grown in California — a state perennially vulnerable to drought.

Each pound of walnuts takes about 1,260 gallons of water, which is less than a pound of almonds or beef (which is kind of in a class by itself, requiring 2,400 gallons of water per pound), but still quite a bit — especially in a water-poor region.

However, walnut trees can also benefit the environment in some important ways. Walnut plantations studied in China increased soil carbon and promoted microbial growth and activities.

And black walnuts are potentially even more sustainable, at least on a small scale, since they are wild-grown and harvested by hand. They require no pesticides and don’t need fossil-fuel-driven machines for harvesting.

Walnut shells also have many industrial uses, some of which are being explored to replace less environmentally friendly alternatives. For example, the shells are being added to substances called geopolymers that can make highly effective insulation.

Walnut shells also have uses as gardening mulch and ground cover, animal bedding, ingredients in the manufacture of activated carbon, abrasive elements in cleaning products, and an energy source for bioethanol production.

Walnuts for the Win

Walnuts are an important tree nut and have been for thousands of years. And while they do use a lot of water, walnuts can also be good for the environment by pulling carbon into the soil. Their impressive nutritional profile makes them a standout for both culinary purposes and medicinal uses. Walnuts are a rich source of healthy fats and protein. And they’ve been found to have benefits for heart, brain, and digestive health, as well as in fighting cancer and inflammation.

For more on how to choose, store, and use walnuts in recipes, check out our article here.

Tell us in the comments:

• How often do you eat walnuts?
• What are your favorite ways to enjoy them?
• What surprised you the most about the health benefits of walnuts?

Featured Image: iStock.com/aslanyus

Read Next:

• You Won’t Believe How Healthy Nuts Are for You
• Are Hazelnuts Good for You? How & Why to Use Hazelnuts

The post Walnuts: Understanding Their Benefits, Nutrition, and Sustainability appeared first on Food Revolution Network.

Plants communicate with us and the world using the language of color as well. While they don’t share romantic sentiments (as far as we know — although I’ve known some blackberry brambles that could get quite handsy), they do give us clues as to their healing powers.

The compounds in plants that enable them to send such signals are called polyphenols. There are over 8,000 of them (at least that we know of), and they belong to a few distinct families. The largest of these families, with over 6,000 compounds (and counting), is flavonoids.

(If you’re eager to read a big honking article all about flavonoids and why they’re so good for you, click here.)

One of the most commonly consumed flavonoids is called quercetin. It’s also one of the most studied. And it’s often touted as a nutrient that can play a big role in the prevention and treatment of heart disease. But what does science say about quercetin? How does it work in the body? Does it have other health benefits aside from cardiovascular? What foods are the best sources? And do you need to supplement to get enough?

Let’s explore the mysterious world of quercetin, and find out all the ways this powerhouse compound is trying to express its love.

What Is Quercetin?

Quercetin is a proud member of the flavonoid family of polyphenols — a class of phytonutrients produced by plants to help them resist fungi, bacteria, and other infections, as well as deter consumption by insects and animals. Quercetin comes in several forms, and one of the most famous among them is rutin.

Rutin has antioxidant and anti-inflammatory effects, and provides some protection against cancer and other diseases. It’s found in high concentrations in buckwheat, and in ginkgo, apples, and other fruits and vegetables.

Rutin, like almost all forms of quercetin, acts as an antioxidant in the body, helping protect you from disease, much like it protects plants from bugs and harmful bacteria. In your body, antioxidants help regulate oxidative stress pathways, preventing and repairing cellular and DNA damage.

Quercetin Health Benefits

Quercetin works on so many systems in the body that it’s no surprise it appears useful in preventing and treating a wide range of conditions. It’s usually easiest for researchers to study a compound when given as a supplement because food comes with a myriad of synergistic variables (such as antioxidants, fiber, calories, and other nutrients) that can impact results. So, most of the research on quercetin has involved supplemental forms. However, keep in mind that, as with most nutrients, food forms are probably best. Here are a few health benefits of quercetin that have been solidly backed up by scientific research (many involving supplementation, for the purposes of the studies).

Quercetin and Heart Health

Quercetin has shown impressive cardiovascular effects in animal and test-tube studies. It lowers blood pressure, reduces cholesterol levels, improves glucose control, prevents the buildup of plaque in arteries, and protects the heart from damage. Clinical trials in humans have found that quercetin can contribute to healthier cholesterol numbers.

A 2016 meta-analysis of seven small controlled clinical trials (with a total of under 600 participants) found a reduction of both systolic and diastolic blood pressure with quercetin supplementation of more than 500 milligrams per day.

One way quercetin can support your heart is by protecting one of the cardiovascular system’s “weakest links:” the endothelial lining of your blood vessels. The endothelium performs a host of essential functions, including helping control the width of your blood vessels and playing a role in blood clotting, inflammation, and immune responses. As it ages, it tends to wear out, and modern drugs and surgical techniques haven’t been able to extend its working life.

Quercetin, on the other hand, appears to protect the endothelium from damage, and in doing so, could help to prevent certain types of heart disease.

Quercetin for COVID-19

Quercetin is known for its antimicrobial, antiviral, anti-inflammatory, antioxidant, and other beneficial effects in the fight against SARS, a coronavirus in the same family as COVID-19.  That’s why scientists have had high hopes for the flavonoid as a means of preventing and treating COVID-19.

Researchers in 2022 found that quercetin did indeed inhibit three parts of the coronavirus cycle of infection: entry, absorption, and penetration. They suggested that it might work synergistically with vitamins C, D, and E as well as other polyphenols as a first-line prevention and treatment protocol for the novel coronavirus.

This was put to the test in a study published in early 2023, in which 50 patients with COVID-19 were given either standard of care or standard of care plus 500 milligrams of quercetin per day. The quercetin group had fewer symptoms than the control group, recovered faster, and tested negative sooner as well.

Some researchers and clinicians are starting to include quercetin in “inventive” drug compositions designed to treat COVID-19, pairing it with vitamins, other phytonutrients, and mainstream pharmaceuticals like Paxlovid.

Quercetin and Cancer

Quercetin appears to disrupt the progression of some cancers, particularly those of the gastrointestinal system, by pushing cancerous cells to self-destruct (a process known as apoptosis). It can also arrest the cycle through which the cancer cells divide and proliferate, as well as inhibit angiogenesis, which is the creation of new blood vessels in a growing tumor.

And that’s just scratching the surface of the ways quercetin appears to mess with cancer. Recently, researchers have been exploring the use of quercetin as an ingredient in “chemoprevention” cocktails that aim to stop cancer before it turns into a clinically significant disease. Preliminary studies have shown that quercetin is lethal to ovarian cancer cells at doses well within the range considered to be safe for daily consumption.

Quercetin for Inflammation

One of the most significant risk factors in the development of cardiovascular disease and type 2 diabetes is obesity. But why? What’s the connection?

Some researchers point to the fact that obesity causes chronic inflammation, particularly in the liver, fat cells, skeletal muscles, and circulatory system. Quercetin’s anti-inflammatory power can lessen insulin resistance (a key driver of type 2 diabetes) and combat atherosclerosis (a big component of heart disease). Also, quercetin helps gut microbiota stay healthy even when dealing with obesity-related inflammation.

A 2020 study found that treating skin cells with quercetin protected them against damage from the inflammation that accompanies skin conditions like atopic dermatitis. Quercetin increased levels of protective compounds (occludin and E-cadherin, if you’re into the details here) and reduced levels of harmful ones (matrix metalloproteinases, to be precise). What’s more, wounds treated with quercetin healed faster, due partly to an increased production of skin proteins and inhibition of the release of enzymes that can degrade skin tissue.

Quercetin’s anti-inflammatory properties suggest that it may also be a powerful booster of the immune system. But as careful scientists love to say, “More research is needed.”

Quercetin and Brain Health

Scientists are also hopeful about quercetin’s potential as a therapy to prevent the progression of neurodegenerative conditions such as Alzheimer’s. It may shield your brain cells from harmful effects caused by unstable molecules (there’s that antioxidant superpower again) while also reducing the breakdown of fats in the brain.

Quercetin also stops the buildup of specific harmful proteins, preventing cell destruction and what’s ominously known as inflammatory cascade pathways.

In addition to Alzheimer’s, other neurodegenerative diseases that are fueled by inflammation include Parkinson’s disease, multiple sclerosis, and amyotrophic lateral sclerosis (ALS). The inflammation in the brain among these disorders can lead to neuronal cell death, with devastating consequences for health, life span, and quality of life.

Recent research has uncovered a possible mechanism by which quercetin can put a stop to this inflammation — by influencing the expression of microRNA. MicroRNA is a small noncoding RNA molecule involved in various biological processes, including development, cell differentiation, and proliferation. Some researchers believe that quercetin’s ability to influence microRNA could be a powerful tool in preventing the damage that accompanies inflammation, and they’re exploring methods of delivering the nutrient in ways that increase its efficacy.

Quercetin Bioavailability

Your body can’t make its own quercetin, so the only way to take advantage of this amazing compound is to get it from food or supplements. If you’re eating a nutritionally excellent diet with a variety of whole plant foods, the good news is that you can expect to consume up to 13 milligrams of quercetin per day.

The less good news is that quercetin bioavailability is generally low. Or at least, humans don’t appear to be very good at absorbing it. All is not lost, though. It turns out that some of your gut microbes are very good at metabolizing quercetin into forms your body can use and benefit from.

There are several ways to increase the bioavailability of quercetin. A 2005 study measured the amount of quercetin in several onion cultivars that were either baked, sautéed, or boiled. Researchers found that baking and sautéing increased quercetin concentrations while boiling decreased them.

You can also absorb more quercetin if you pair quercetin-containing foods with a fat source. That’s because quercetin dissolves in fat, which is why it’s known as lipophilic. And having those foods along with sources of water-soluble fiber, such as pectin and soybeans, may also improve quercetin bioavailability.

Finally, quercetin is more bioavailable when consumed as part of a whole food. That is to say, your body appears to recognize it and know what to do with it when it is delivered in a familiar package, together with all the other phytonutrients contained in that food.

Food Sources of Quercetin

Should You Take Quercetin Supplements?

Since quercetin is in so many different plant foods, for most people, supplements are probably not necessary — especially since whole-food sources appear to be more bioavailable.

There might be some instances, however, in which quercetin supplements could be beneficial. For someone suffering from chronic inflammation, supplemental quercetin may help. And studies have shown that it can inhibit histamine production and pro-inflammatory mediators, which could help allergy sufferers.

A 2016 study of rats who had had noxious chemicals sprayed into their nostrils found that supplementing at 25 milligrams per kilogram of body weight for at least five days reduced nasal rubbing and sneezing. (Our view on the use of animals in medical research is here.)

As we’ve seen, quercetin supplementation can reduce the length and seriousness of COVID-19, especially if administered at an early stage. It may also be able to improve performance and recovery in athletes, who seem to need more antioxidants than other people to counter the oxidative damage brought on by intense physical exertion.

In terms of safety, clinical trials of supplemental quercetin have shown no significant side effects with doses of up to 1,000 milligrams per day for up to 12 weeks. As quercetin isn’t very bioavailable to begin with, supplements often include another bioactive compound that can help with absorbability. Quercetin may be absorbed more effectively when combined with bromelain, zinc, and/or vitamin C.

Side Effects of Quercetin Supplements

The most common side effects of quercetin supplements are headache and upset stomach.

In terms of drug interactions — quercetin can impact how the body responds to certain medications, including blood thinners, antibiotics, and other drugs with a similar chemical structure. Quercetin may also interact with chemotherapy drugs used to treat cancer. Whether it improves their effectiveness or gets in their way is still up for debate.

And in female rats with estrogen-induced breast cancer, even dietary quercetin was problematic, as it increased tumor severity. However, it remains to be seen whether the same can be said for humans.

Since studies show that quercetin can significantly lower blood pressure and may protect cardiovascular health, it may enhance the effects of blood pressure and blood-thinning medications. Therefore, it’s probably best to talk with your health care provider before starting quercetin supplementation if you’re taking these types of medications.

Recipes with Quercetin

From delightful salads featuring quercetin-packed blueberries to a hearty dish that incorporates quercetin-rich artichokes, these recipes provide delicious ideas for how to enjoy everyday quercetin-filled foods. Enjoy the healing benefits of quercetin to help nourish your heart health, immune system, brain function, and more — all while indulging in plenty of delicious whole food, plant-based ingredients!

1. Cinnamon Apple Breakfast Smoothie

Indulge in our Cinnamon Apple Breakfast Smoothie, a delightful morning treat that not only tantalizes your taste buds but will also boost your day with quercetin and other vital nutrients. At the heart of this smoothie lies the unassuming apple, packed with quercetin, a potent flavonoid renowned for its antioxidant prowess. By including an apple in your smoothie, you’re also inviting the goodness of quercetin to join the party, enhancing both flavor and nutrition.

2. The Shine Brightly Salad

We just love how The Shine Brightly Salad can’t help but put a smile on people’s faces. The addition of sweet and juicy blueberries is one big reason why! Blueberries are bursting with quercetin, which is your ally in the fight against oxidative stress and inflammation. Plus, when combined with fresh leafy greens and toasty sunflower seeds, you’ll enjoy a fresh and vibrant salad that will help you shine from the inside out!

3. Cheesy Artichoke and Asparagus Penne

Artichokes are among the top quercetin-rich veggies — and boy, oh boy, do we love them (and hope you do, too!). This Cheesy Artichoke and Asparagus Penne is loaded with powerful antioxidants, phytochemicals, and essential minerals like magnesium, potassium, niacin, and folate. Adding artichokes to your diet regularly is a great way to lower inflammation and increase healing through plant power. What’s more, this colorful pasta has tons of fiber from the veggies, whole grains, and lentils, as well as protein from the lentils — so you’ve got the complete package when it comes to this meal.

Embrace the Power of Quercetin

Quercetin, a compound found in some of our most popular fruits and vegetables, is a powerhouse of nutritional goodness. Thanks to its antioxidant, anti-inflammatory, and immune-boosting abilities, it appears to be something of a dietary medicine cabinet in a single nutrient.

Some people, such as athletes and those suffering from respiratory illnesses like COVID-19, may benefit from supplementation. But for most people, eating a varied and balanced diet will allow you to get the quercetin (and other phytonutrients and antioxidants) you need to optimize your health.

Tell us in the comments:

• Which colors of the “food rainbow” do you want to eat more often?
• What are your favorite quercetin-containing foods?
• Which quercetin-rich recipe will you try next?

Featured Image: iStock.com/Marko Jan

Read Next:

• What Are Flavonoids? And How Are They Good for Your Health?
• Eat the Rainbow: Why Is it Important to Eat a Colorful Variety of Fruits and Vegetables?

The post Quercetin: Health Benefits, Risks, and Sources Compared appeared first on Food Revolution Network.

What do you do to stay alive and thrive in the face of all these challenges? If you answered “synthesize polyphenols,” then congratulations! You’ve just won this round of “Are You as Smart as a Plant?”

Polyphenols are a class of compounds (a huge class, actually, made up of at least 8,000 different ones that we know of) that are in a wide variety of plant foods. You may have heard of some of them, like resveratrol (found in grapes and red wine) and EGCG (featured in green tea).

Plants produce them as protection from various threats, including disease and sun damage. And animals who consume those plants can also benefit from polyphenols in similar ways.

As industrialized societies struggle to contain multiple epidemics of chronic disease, many medical experts and researchers are now pointing to polyphenols (and other nutrients found in whole, minimally processed plant foods) as powerful allies in preventing and treating a variety of chronic conditions.

So in this article, we’ll explore the world of polyphenols, including how they work in your body, their health benefits, and whether you should get them from food or supplements.

What Are Polyphenols?

Polyphenols are natural compounds found in various plants. Researchers consider polyphenols to be kind of “bonus” compounds, or in their jargon, “secondary metabolites.” This means they’re not directly involved in the growth, development, or reproduction of a plant.

Plants produce polyphenols as a defense mechanism against ultraviolet radiation and aggression from pathogens. But they aren’t purely defensive; they’re also deployed to attract pollinators.

From our perspective, polyphenols play a significant role in the flavors and health benefits that many plant foods offer. They can change the way plants taste, and determine their colors and aromas.

Polyphenols are also antioxidants, so their presence can keep plant foods from rotting (a trick known as “oxidative stability”). They also can help prevent oxidative stress in your body after you consume them, which can help stave off many types of disease.

There are several subfamilies of polyphenols, including flavonoids, phenolic acids, and lignans. In addition to resveratrol and EGCG mentioned above, another well-studied polyphenol is curcumin, found in turmeric root and powder.

What Are the Health Benefits of Polyphenols?

The “poly” in polyphenol means that all compounds in this family have multiple phenolic hydroxyl groups — but could just as easily refer to their ability to prevent and treat multiple health conditions.

Polyphenols and Cancer Prevention

Both test-tube and animal studies suggest that polyphenols can help prevent the initiation and progression of several cancers. They do this via a number of mechanisms, including inhibiting the proliferation and spread of cancer cells, suppressing tumor growth, preventing the formation of new blood vessels, and fighting inflammation.

Different classes of polyphenols exhibit different anticancer properties. For example, flavonoids, including quercetin and kaempferol, can inhibit cancer cell growth and induce cancer cell death. Resveratrol suppresses tumor growth, inhibiting metastasis and reducing angiogenesis. And curcumin, derived from turmeric, is multitalented; it’s anti-inflammatory, antioxidant, apoptotic, antiangiogenic — and a bunch of other words that don’t begin with A.

Many forms of polyphenols are also known to influence critical signaling pathways that are integral to the initiation, advancement, and spread of cancer.

And polyphenols aren’t just cancer fighters on their own; they’re also team players. Researchers have found that polyphenol combinations are more powerful than the effects of each one individually. For example, a mixture containing quercetin, curcumin, green tea, Cruciferex (a proprietary blend of polyphenols found in cruciferous vegetables), and resveratrol significantly inhibited the growth of a particular cancer of the head and neck.

Polyphenols and Heart Health

Polyphenols can also protect your heart in a bunch of different ways. They reduce cardiac inflammation and oxidative stress, support cell mitochondria in doing their job properly, and increase survival signaling (the ways cells talk to each other when they encounter a potential threat).

Some polyphenols have also been found to reduce the formation of blood clots, which decreases the risk of heart attacks and strokes. And the flavonoid family of polyphenols promotes the dilation of blood vessels, which helps lower blood pressure and improve blood flow — both of which help with cardiovascular health.

Polyphenols can also improve your cholesterol profile — specifically, lowering LDL and increasing HDL cholesterol levels, thereby reducing the risk of atherosclerosis.

Some polyphenols are not easily absorbed by your small intestine, but it turns out that these polyphenols can be metabolized by the microbes in your gut into compounds that contribute to cardiovascular health.

Impressed by these myriad beneficial mechanisms, some researchers are now studying therapeutic protocols for using polyphenols in medicine to prevent and treat cardiovascular disease.

Polyphenols and Diabetes

One of the most dangerous consequences of diabetes can be vascular disorders, where persistent high blood sugar levels cause damage to blood vessels through inflammation, oxidation, and cell death. Polyphenols can combat all three mechanisms. And scientists are exploring how to use them to modulate the expression of the genes involved in the development of vascular conditions.

Human and animal studies (our views on the use of animals in medical research can be found here) show that polyphenols can lower high blood sugar levels and enhance the body’s ability to secrete insulin quickly and respond to it effectively.

It appears polyphenols accomplish this via several mechanisms. They slow down how quickly your body absorbs sugar from the food you eat. And they encourage your pancreas to produce more insulin in response to carbohydrate consumption. They also regulate how much glycogen the liver releases into your blood in the form of sugar.

If all that wasn’t enough, polyphenols also help insulin receptors work more efficiently and help tissues absorb more sugar than they would otherwise.

Polyphenols also fight diabetes by helping to protect pancreas cells that produce insulin from damage due to high glucose levels. They also promote the growth of these cells and slow down their death.

Polyphenols and Osteoporosis Benefits

As you age, you lose bone mass — that’s natural. But your diet and lifestyle can significantly influence the rate at which that happens. In some people, the process accelerates due to oxidative stress messing with the living tissues in bone: the osteoblasts and osteoclasts that build and break down bone, respectively.

Since polyphenols are such powerful antioxidants, researchers theorized that eating berries (one of the richest food sources of the compounds) could help reduce bone loss due to stress and aging. And they might have been on to something because several studies have now shown that people who eat a lot of berries also have higher bone mass. Since the standard pharmaceutical treatments for osteoporosis have a high rate of serious side effects, there’s a lot to be gained by exploring how eating polyphenol-rich foods can help prevent or slow bone loss.

In addition to oxidative damage, it appears that bone loss can also be caused by inflammation. A 2019 literature review found evidence that polyphenol-containing foods like fruits, vegetables, tea, and soy may combat osteoporosis by reducing inflammation, thus allowing the body’s bone remodeling process to proceed without hindrance.

A 2023 study out of Korea also found concrete evidence for the link between high polyphenol intake and protection from osteoporosis. Researchers gave bone density tests and food intake questionnaires to 4,600 women and followed up with them for an average of five years. They found that the postmenopausal women who reported eating the most phytochemical-rich foods (i.e., those high in polyphenols) had a 16% lower risk of developing osteoporosis than those who ate the least.

Polyphenols and Brain Health

One of your body’s most important functions goes by the strange name autophagy, which literally means “eating oneself.” Instead of visualizing someone chomping on their own arm, however, think of your tissues constantly absorbing and discarding malfunctioning cells, proteins, and other bits and bobs that are no longer doing their jobs. This process in the brain is key in protecting you from neurodegenerative diseases such as Parkinson’s, MS, ALS, Huntington’s, Alzheimer’s, and other types of dementia.

Research shows that polyphenols support the brain’s clean-up process by removing misfolded proteins. They also reduce brain inflammation and stress, helping protect the brain from damage that can lead to neurodegenerative conditions.

Polyphenols are especially suited to supporting your cognitive health for several reasons. First, unlike many other nutrients, they can easily pass into your brain from your bloodstream (crossing that very finicky blood-brain barrier). Second, they help to remove harmful substances known as reactive oxygen species that can damage your brain cells. Third, they can capture and neutralize certain metal ions, such as copper and iron, that could be harmful to your brain in high concentrations.

But wait — there’s more! Polyphenols have another special brain ability: They can increase the amount of neurotrophic factors in your brain that promote the health and growth of your nerve cells. By attaching themselves to the receptors of these neurotrophic factors on the surface of nerve cells, polyphenols enhance the cells’ abilities to adapt, survive, multiply, and grow. It appears, in fact, that polyphenols can not only protect your brain from degeneration but may even support learning, memory, and other cognitive abilities.

Is There an RDA for Polyphenols?

Given how awesome polyphenols are, you might think that government bodies tasked with setting nutritional standards would have come up with a recommended daily allowance (RDA). But no such standard exists in the US because the compounds aren’t considered “essential” nutrients — that is, there aren’t any diseases specifically caused by a deficit, the way insufficient vitamin C leads to scurvy and not enough B1 inevitably produces beriberi.

Instead, not getting enough polyphenols can shorten a lifespan by making a person more likely to develop one of the chronic diseases mentioned above. For example, a 2013 study found that people who consumed more than 650 milligrams of polyphenols per day had a 30% lower chance of dying in any given year compared with people who got less than 500 milligrams per day.

So instead of a numerical RDA, the quasi-governmental Food and Nutrition Board of the Institute of Medicine recommends five fruits and/or vegetables a day, which theoretically would give you a significant amount of polyphenols. And if you “eat the rainbow” pretty much every day — that is, consume foods of many different colors (and no, Skittles don’t count) — you’ll also therefore get a wide range of polyphenols.

What Foods Are Rich in Polyphenols?

What Influences Polyphenol Amounts?

Unfortunately, you can’t simply look up a food’s polyphenol content in an online database and know exactly how much you’ll get when you eat that food. And even if you could, there are various factors that can influence how much you actually absorb.

Polyphenol Bioavailability

On the whole, polyphenols tend to have low bioavailability, which means your body can absorb and use only a small percentage of what you swallow.

The exact conversion ratio is based on many factors, including the health and makeup of your gut microflora. Since your microbiome can change on a constant basis, depending on what you feed it, how much of the polyphenols in your food you can actually get into your cells may also vary widely from day to day.

Also, the different polyphenols differ greatly in how bioavailable they are. The most abundant dietary polyphenols typically have lower absorption rates than less common ones.

Food Handling Impact

How plant-based foods are processed, stored, and cooked also strongly influences their polyphenol content.

If you remove the peels and hulls of certain foods, you can lower their polyphenol content. On the other hand, macerating (such as in a blender or food processor) some foods can increase their polyphenol content.

When it comes to food storage, the cold storage of apples, pears, and onions appears to maintain high polyphenol levels. But when cut fruits turn brown, which tends to happen if they are exposed to air, they begin to lose polyphenols.

Many foods lose polyphenol levels with time. For example, in wheat flour, concentrations of polyphenols drop by about 70% after six months. But black tea actually increases its polyphenol content after some oxidation.

Some polyphenol levels also increase with cooking, while others decrease — it depends on the food, the particular polyphenolic compound, and the cooking method. For example, onions and tomatoes lose between 75% and 80% of their initial quercetin content after boiling for 15 min, and 65% after cooking in a microwave oven.

So Should You Take Polyphenol Supplements?

A limited amount of research has indicated that people may possibly see benefits from polyphenol supplements. For example, athletes who were experiencing physiological stress were given polyphenol supplements, and they experienced some benefits in performance and recovery.

But the evidence is a bit murky: Many researchers don’t use pure polyphenols or mixtures, but add in other antioxidants — so it’s hard to know how much of the benefit is coming from the polyphenols, the other active ingredients, or some synergistic interaction of multiple elements.

There’s also not a lot of safety data available about these supplements. And as polyphenol marketing gives these compounds their place in the sun, some manufacturers are taking advantage of their popularity to create mega-dose formulations that have never been tested for safety or efficacy.

Because research on the benefits of polyphenols typically uses amounts much higher than those commonly found in human diets, we just don’t know the levels at which they are safe and beneficial for human consumption.

Some supplements (including those containing polyphenols) could cause liver damage in high doses, and may also block the absorption of nonheme iron, which is an essential nutrient.

Perhaps the best argument against supplementation is that it’s probably completely unnecessary for most people, as polyphenols are abundantly available in a wide variety of fresh and healthful foods.

Plus, just like every other plant-based antioxidant and phytonutrient, polyphenols work better in harmony with other nutrients that naturally occur in food. And when you consume whole plant-based foods, you also get the benefit of fiber and other health-promoting micronutrients.

In general, most people are better off getting their nutrition from food rather than from supplements, and there’s no reason to think that polyphenols are an exception.

Polyphenol Recipes

From bitter to salty, from sweet to tart, polyphenols are in abundance in many of your favorite plant-based foods. These delicious and nourishing polyphenol recipes are a great way to experiment with and incorporate them into your daily meal routine.

1. Banana Tahini Coffee Smoothie

Coffee is a plentiful source of polyphenols as it contains chlorogenic acids, which fight free radicals and prevent oxidative stress damage, making it a potent antioxidant-rich ingredient. Not only does it give you a burst of energy — you get a powerful health boost, too! Together with creamy banana, nutty tahini, nutrient-rich cauliflower, and sweet spices, this Banana Tahini Coffee Smoothie is an easy-peasy and ultra-creamy way to enjoy polyphenols.

2. Apple Walnut Sage Dressing

Apples have an abundance of polyphenols, more specifically anthocyanins, flavanols (catechins), flavonols (quercetin, rutin), chlorogenic and caffeic acids, and dihydrochalcones, which can help to reduce inflammation, support your immune system, and even help with seasonal allergies! We don’t think you’ll need any more convincing, but this creamy Apple Walnut Sage Dressing is an inflammation-fighting, health-promoting, and deliciously sweet and savory sauce that is the perfect polyphenol-rich addition to your favorite summer or fall salad.

3. The Shine Brightly Salad

We love The Shine Brightly Salad for many reasons. And the addition of sweet and juicy blueberries is a major factor! Blueberries are loaded with anthocyanins, resveratrol, and flavonols (quercetin), which are all under the umbrella of polyphenols. You’ll also get a hefty dose of health-promoting spinach, red onion, sunflower seeds, and lemon juice. With so many colorful plant foods combined, you know you’ll be getting a wide variety of phytochemicals, antioxidants, and other polyphenols that will keep your body in tip-top shape — and shining brightly from the inside out!

Eat More Plants to Reap the Benefits of Polyphenols

From fending off cancer and heart disease to supporting healthy blood sugar levels and bone density, polyphenols are like real superheroes of our dietary choices, working tirelessly to safeguard our well-being. These compounds are readily available in a wide array of whole foods.

While some individuals may find benefit from polyphenol supplements, on the whole, the safety and efficacy of high-dose polyphenol supplements remain unclear. So it’s probably best to get your polyphenols from food. And let your plate be a canvas of color and flavor, celebrating the goodness that polyphenols have to offer.

Tell us in the comments:

• What are your favorite foods from each color of the rainbow?
• Are there polyphenol-rich foods that you’d like to add to your diet?
• Which recipe will you try next?

Featured Image: iStock.com/Aiselin82

Read Next:

• What Are Antioxidants? And What Are the Most Antioxidant-Rich Foods?
• Quercetin: Health Benefits, Risks, and Sources Compared

The post Polyphenols: Nature’s Prescription for a Healthier You appeared first on Food Revolution Network.

Prices for copper rose in the 1970s largely due to the electronics revolution. Copper is a great conductor of electricity. So as the need for wiring and components increased, global demand did, too.

Copper’s properties also make it not just valuable but indispensable for human health. It doesn’t get the same press as other minerals, such as calcium and iron. But it serves many crucial functions in the body.

In this article, we’ll explore why copper is necessary for bodily functions ranging from immune support to antiaging properties to brain protection. We’ll discuss the potential risks of not getting enough copper, and whether that’s a concern (especially for plant-based eaters), as well as the very real dangers of getting too much copper.

What Is Copper?

Copper is an essential trace mineral found in every tissue of your body. Like other minerals, your body doesn’t make its own; you need to get it from food. But compared to many other essential minerals, you don’t need a lot for optimal functioning.

Copper is a very busy do-gooder in your body, lending a hand all over the place. It’s a cofactor (a nonprotein molecule that supports a biochemical reaction) for several enzymes known as cuproenzymes (“kupros” is Greek for copper, so named because the island of Cyprus was famous for its rich copper deposits). These enzymes are involved in the production of energy, neurological signaling, and the making of connective tissue.

Copper helps your body form collagen and assists in iron absorption. It also acts as an antioxidant. The main defense against oxidative stress actually involves copper-based compounds called superoxide dismutases (SODs for short). SODs help convert superoxide radicals into less harmful molecules like oxygen and hydrogen peroxide.

Copper is also involved in the formation of new blood vessels. Plus, it helps balance various neurohormones, regulates gene expression, supports brain development, influences skin pigmentation, and maintains the functioning of the immune system. That’s one busy mineral!

How the Right Amount of Copper Benefits Your Health

Copper is essential for many bodily processes but harmful in both deficiency and excess. (Or as Goldilocks might say, “Not too little and not too much, but just right.”) Maintaining appropriate copper levels is important for overall well-being. And it’s particularly important for the health and functioning of your brain, bones and joints, heart, arteries, skin, and immune system.

Let’s look at some of the ways that researchers study copper in regard to health.

Copper and Heart Health

Proteins containing copper are essential for protecting your cardiovascular system from stroke and the damage it can cause. When the body doesn’t manage copper levels properly, it can lead to heart problems, including enlargement, heart failure, coronary artery disease, and a type of heart disease related to diabetes.

But for most people, too much copper is a more likely problem than not getting enough. A 2015 study compared copper levels in 334 people, some of whom had healthy arterial function and some with varying degrees of atherosclerosis (arterial hardening and blockages). Researchers found higher blood levels of copper in the patients with atherosclerosis. And the more severe the condition, the higher the levels of copper.

Because of the study design, we can’t say whether the high copper levels caused the atherosclerosis or if it was the other way around. (Or, for that matter, if both stem from something else.)

Copper and Brain Health

The right amount of copper is also necessary for brain development and function. Diseases that affect brain copper levels, such as Menkes disease (not enough copper) and Wilson disease (too much copper), affect the functioning of neurotransmitters called catecholamines. They play a role in various brain functions, such as regulating mood, motivation, attention, and stress response. And they’re involved in transmitting signals between neurons and can affect cognition and behavior.

Elevated copper levels may also play a role in the development of Alzheimer’s disease. Studies have shown high levels of copper can affect the functioning of neurons in important areas of the brain, such as the hippocampus and cerebral cortex. This can lead to problems with memory, critical thinking, and motor skills.

Researchers have also discovered a connection between copper and the formation of amyloid beta plaques, which are a hallmark of Alzheimer’s disease. As copper levels increase, it can speed up the formation of these plaques, contributing to further damage in the brain.

Copper and Bone Health

Too much or too little copper is also a problem for your bones and joints. Copper compounds are important cofactors for an enzyme that makes bone matrix (basically, the stuff that makes up your bones). And nearly two-thirds of the copper in your body is stored in muscles and bones.

In 2014, researchers looked at 50 adults who had severe tooth wear (that means their teeth were worn down, not that their teeth wore high-necked cardigans and ankle-length skirts). They found lower copper levels in their tooth enamel, as well as lower bone mineral density in the spine, which is a predictor of osteoporosis.

A 2018 study measured copper levels in participants’ blood and also looked at several aspects of bone health, including bone mineral density and whether they had fractured any bones. Researchers found that people with lower levels of copper had lower bone mineral density in certain areas of the hip compared to those with slightly higher levels of copper.

They also found that those with very high levels of copper in their blood had a higher risk of experiencing fractures compared to those with slightly lower levels. So again, copper adheres to the Goldilocks principle.

Copper and Skin Health

It’s time to introduce you to a very special substance in your blood: glycyl-L-histidyl-L-lysine. That’s a mouthful, so we’ll follow the scientists in calling it GHK.

GHK levels are highest when you’re young, around 20 years old, but decrease as you get older. By the time you’re 60 years old, the levels drop significantly.

GHK has a special attraction to copper, and when they come together, they form something called GHK-Cu. GHK-Cu can help rejuvenate your skin by promoting the growth of new skin cells and speeding up the healing process. It has powerful antioxidant properties, which means it helps protect your skin from the sun and other oxidative damage. And it can also reduce inflammation in the skin, which can help prevent and smooth out wrinkles.

Did you know your skin can absorb copper? Studies show that there’s a low risk of adverse reactions from skin absorption of copper. And several placebo-controlled clinical trials have shown that sleeping on pillowcases impregnated with copper oxide can actually reduce the depth of facial wrinkles and improve overall skin health.

A 2020 study took small skin grafts and exposed them to these fabrics. The researchers found that they continuously released copper ions that were absorbed through the skin, which increased the production of some skin proteins, stabilized the dermal layer, and reduced aging and damage.

Copper and the Immune System

Copper is also required for the formation and activity of neutrophils, a type of white blood cell that’s a key component of the immune system. Their main role is to defend the body against infections caused by bacteria and fungi.

But there’s a downside to copper’s ability to support immunity: There’s an association between excess copper levels and increased immunity of cancerous tumors to treatment. So how difficult is it to get the right amount of copper for good health?

How Much Copper Do You Need?

Since copper is a trace nutrient, only a small amount is necessary daily. And only a small amount is stored in the body. Whereas iron or calcium requirements are in milligrams per day (mg/day), copper needs are in micrograms per day (mcg/day). A microgram is one-millionth of a gram, which is a very, very tiny amount indeed.

The following are the United State’s RDAs (Recommended Daily Allowances) for copper at different stages of life.

So those are the recommended minimum levels. What about maximums? Officially, the upper limit of copper for adults is 10,000 mcg per day. But it may also be the case that the official maximum levels should be lower. As many scientists are fond of saying, “More research is needed.”

Dietary Copper Sources

Copper is in a variety of foods. And the foods highest in copper are animal-derived products such as organ meats, oysters and other seafood, poultry, and red meat. Meat products are the only foods that will put you anywhere near the upper limit of 10,000 mcg per day. For example, three ounces of pan-seared beef liver has over 12,000 mcg of copper.

But you don’t have to eat animal products to meet your RDA of copper. Many plant-based foods are good sources of copper, too.

Here are some of the top plant-based sources of copper:

Copper Deficiency

If clinical copper deficiency is present, symptoms can include anemia (not enough red blood cells and/or not enough hemoglobin in the blood), bone and connective tissue abnormalities, and neurological problems.

But since so many foods contain copper, deficiency is generally less about intake and more frequently due to intestinal problems (such as Celiac disease) or genetic conditions. Maintaining adequate copper levels in the body is mostly dependent on absorption from the intestines. As a result, copper deficiency is relatively uncommon among the general population.

Your body also has the ability to modulate its copper absorption rate based on availability. It generally increases the absorption rate if your diet contains less copper.

However, copper levels are not typically assessed in routine testing as there isn’t a reliable biomarker for copper status. Blood levels of copper and ceruloplasmin (CP) concentrations are sometimes used in people with a known deficiency (such as with Menkes disease). But factors such as infection, pregnancy, and even some cancers can affect the accuracy of these levels.

Zinc Supplementation and Copper

However, there’s a cause of copper deficiency that is in your control and has been seen more frequently since the start of the COVID-19 pandemic: zinc supplementation. Zinc was one of many dietary supplements recommended during the height of the pandemic as a means to bolster immune defense.

While zinc can help prevent and fight infections, there is the issue of too much of a good thing. Excessive zinc intake (more than 50 mg a day) has been shown to interfere with the body’s absorption of available copper. As a result, copper levels in the body can drop to dangerous levels and cause symptoms of deficiency.

High doses of vitamin C (over 1,500 mg a day) or supplemental iron may also induce copper deficiency by competing with copper for absorption in the intestine. This is one reason to be cautious about taking large amounts of supplements on an ongoing basis.

Copper Toxicity

There are also a few ways to have dangerously high levels of copper in your body. That condition is most frequently associated with Wilson disease, a rare inborn error of metabolism that starts by overloading the liver with copper, and then moves on to the brain and other tissues.

People can also get acute copper poisoning from drinking beverages stored in copper-containing containers, as well as from contaminated water supplies. The US Environmental Protection Agency has set upper limits on copper in drinking water at 1.3 milligrams per liter, while the World Health Organization is okay with the slightly more lenient 2 milligrams per liter.

Copper can enter your drinking water through corroded copper pipes, so if you live in an old house or have well water, you may want to get your water tested.

Excessive amounts of copper can cause abdominal pain, nausea, vomiting, and diarrhea in the short term. Long-term copper overexposure can cause liver damage and kidney failure.

You can also get copper poisoning by cooking food, especially acidic food like tomato sauce, in uncoated copper cookware. (Many chefs love this cookware because copper is an excellent conductor of heat.) The good news is, most copper cookware is lined with a nonreactive metal, such as nickel, tin, or stainless steel. As long as you take care of the lining by cleaning it with nonabrasive materials, and stop using it if the lining starts to crack or flake, copper cookware can be perfectly safe.

Toxicity from Copper Supplementation

Another cause of copper toxicity is taking copper-containing supplements. Some of the most commonly found multivitamins contain copper. And some even contain over double the RDA for copper. But copper supplementation is not generally recommended.

Health care professionals like Dr. Neal Barnard actually advise against the inclusion of both iron and copper in multivitamins. Too much of either can negatively impact brain health, possibly even contributing to the development of neurological disorders like Alzheimer’s and Parkinson’s. One 2022 study based on the Atherosclerosis Risk in Communities (ARIC) cohort found that “Copper intake from supplements was associated with greater 20-year decline in global cognition overall.”

However, the amount of copper in multivitamins and other supplements isn’t the only reason there’s a risk of toxicity. It’s also because the average copper intake among US adults already exceeds the recommended amounts. With so many foods providing an abundance of copper, especially animal products that are commonly consumed as part of the modern industrialized diet, there’s no need for added copper supplementation.

In fact, getting copper from animal products may be just as bad or even worse than getting it from supplements. That same 2022 study found that dietary copper, especially when consumed with saturated fat, increased the risk of incident dementia. And since plant-based foods have lower copper bioavailability and saturated fat, there’s no known neurodegenerative effects (and less risk of copper toxicity).

Copper-Rich (But Not Copper-Excessive) Plant-Based Recipes

Goldilocks would be happy with these tasty (and simple to prepare) plant-based recipes. From savory breakfast wraps to naturally sweet chocolate chip muffins, meeting your copper needs (without risking exceeding them) on a plant-based diet can be easy (and delicious)!

1. Tofu Scramble Breakfast Wrap

Tofu Scramble Breakfast Wrap is a delicious morning meal that not only satisfies your taste buds but also prioritizes your nutritional well-being. You’ll get your daily copper needs met from the tofu, spinach, and avocado in this wrap. Plus, you also get the added benefits of fiber, plant-based protein, healthy fats, and plenty of other essential nutrients. This wrap is a hearty and savory way to start your day the plant-based way!

2. Green Goodness Sandwich

Green Goodness Sandwich practically overflows with fresh, colorful, and nutrient-rich veggies. The green veggies — leafy greens, cruciferous vegetables, and avocados — are all great sources of plant-based copper. And this sandwich is also piled high with other colors (which means lots of phytochemicals!) — from red tomatoes to purple onion to orange turmeric to white seeds. This nourishing meal is bursting with so much wholesome goodness, you may want to add it to your regular recipe rotation.

3. Banana Chocolate Chip Millet Muffins

Dark chocolate and millet are the copper-rich, plant-based stars of these Banana Chocolate Chip Millet Muffins. Whether you enjoy the muffins as a wholesome breakfast or an afternoon pick-me-up, you can take pleasure in knowing that you’re getting the nutrients your body needs. Indulge in the delightful flavor and nutritional benefits of Banana Chocolate Chip Millet Muffins — because a little copper can go a long way toward a healthier you!

Getting the Right Amount of Copper is Key

Although it doesn’t get the same attention as many other nutrients, copper is essential to health and vitality. It works as an antioxidant — combatting oxidative stress throughout your body. And it has research-backed benefits for your heart, brain, bones, skin, and immune system.

But too much copper can be a problem, and this may be more of a concern for people who eat large amounts of animal products that are especially high in it, take supplements with copper, or whose drinking water is contaminated with copper from pipes. The good news is that it seems most people who eat a plant-based diet will do just fine with their copper consumption. And that should please Goldilocks very much.

Tell us in the comments:

• Penny for your thoughts! What did you find surprising about copper and nutrition in this article?

• What’s your favorite copper-containing plant-based food?

• Which recipe will you try next?

Featured Image: iStock.com/ratmaner

Read Next:

• Zinc: Benefits, Risks, & How Much You Need

The post Dietary Copper: How Much Copper Should You Get and the Best Sources of Copper appeared first on Food Revolution Network.

In this article, we’ll embark on a journey to demystify the realm of antioxidants, delving into what they are, the types of antioxidants, and why they’re essential for our well-being.

Join us as we uncover the vibrant world of antioxidants and unveil the top foods and beverages that deliver a potent dose of these health-enhancing compounds.

Oxidation and Free Radicals

“Antioxidant” is a scientific term that literally means “substance that inhibits oxidization.” So in order to understand antioxidants, it helps to first understand oxidation and what happens during this process.

Oxidation happens naturally as your cells process the oxygen you breathe and convert it into energy. During this process, electrons pass along a series of molecules in something called cellular respiration. However, some electrons break free and become unpaired, damaging cells and DNA in their search for other electrons.

Molecules with one or more electrons are called free radicals.

Some free radicals form during natural processes like inflammation from an acute injury. But others develop in response to external factors like fried foods, alcohol, tobacco smoke, pesticides, pollutants in the air, and eating an unhealthy diet.

While free radicals aren’t inherently bad (your body uses them for certain processes, like fighting off problematic bacteria), they are highly unstable and can cause damage to your DNA, proteins, and cell membranes. The key is to have a balance — enough free radicals for their useful functions but not so many as to cause damage. When there are too many free radicals, they overwhelm the body’s natural repair processes and cause health problems.

Oxidative Stress and Antioxidants

A buildup of too many free radicals in the body is known as oxidative stress.

Oxidative stress is thought to be a leading cause of age-related and non-age-related deterioration and disease, including memory loss, the breakdown of organs, autoimmune disorders, heart disease, type 2 diabetes, cancer, and even wrinkles.

And that’s where antioxidants come into play. They are the good guys in the fight against excessive free radicals and subsequent oxidative stress. Antioxidants neutralize free radicals from oxidation by giving them the electrons they need to stabilize.

This is not just a one-and-done situation, however. Every day, your body is creating free radicals. So you need to consume antioxidants daily in order to keep your cells healthy and in balance. Without antioxidants, free radicals would build up and create significant oxidative stress, putting you at higher risk for a number of chronic diseases and other health issues. This is called oxidative debt.

What’s the Solution to Oxidative Debt?

It’s estimated that we need between 8,000 and 11,000 antioxidant units per day to avoid a deficit. But the average American doesn’t even get half the minimum recommended amount of antioxidants.

This deficiency may be part of the reason why oxidative stress-related diseases, such as heart disease, type 2 diabetes, and certain types of cancer, are so prevalent in industrialized countries.

The solution? We need to consume more antioxidants.

What Are the Different Kinds of Antioxidants?

There are thousands of substances that act as antioxidants in the body. However, not all antioxidants are interchangeable or operate exactly the same way. Some antioxidants excel at fighting certain types of reactive oxygen species (ROS), such as free radicals, while others are effective only in specific parts of your cells.

Your body naturally produces some antioxidants, but most of them have to come from your diet.

While most foods contain some antioxidants, plant foods are the primary source. On average, plant-based foods contain 64 times more antioxidants than animal-based foods.

So what are the most important antioxidants to pay attention to?

Vitamin E

While there are eight forms of fat-soluble vitamin E, α-tocopherol is the most bioactive form of this antioxidant in humans. Vitamin E supports cardiovascular health and immune function, and is good for your eyes, skin, and brain. But it’s necessary to get it from food rather than supplements to reap its benefits. Top food sources include nuts, seeds, avocado, bell peppers, and mango.

For more on vitamin E, including the best sources, see our article, here.

Vitamin C

This crucial water-soluble antioxidant has actually been shown to regenerate other antioxidants. While it’s best known for preventing scurvy and maybe the common cold, vitamin C is also necessary for collagen production and can protect your skin from the sun. Top food sources include citrus fruits, bell peppers, broccoli, papaya, and brussels sprouts.

To find out more about the benefits of vitamin C, see our article, here.

Vitamin A

Technically, vitamin A is a group of compounds known as fat-soluble retinoids, rather than a single vitamin. Together, these compounds make up vitamin A, which is an important antioxidant for eye health specifically, as well as immune support and reproductive health. There are both active forms and precursors available in food, the former mainly being in animal products while the latter are found in plants.

Plant-based vitamin A compounds are called carotenoids and include beta-carotene and lycopene, as well as lutein and zeaxanthin. While not all of these carotenoids convert to vitamin A, they are all important antioxidants for good health.

For more on vitamin A and carotenoids, see our article, here.

• Beta-carotene — This red/orange plant pigment combines with other elements to form vitamin A in your body. Top food sources include carrots, sweet potatoes, winter squash, spinach, kale, cantaloupe, and apricots.
• Lycopene — This fat-soluble antioxidant can mostly be found in red- and pink-hued foods. The most famous source is tomatoes, but it’s also found in watermelon, pink grapefruit, pink guava, papaya, and goji berries.
• Lutein and Zeaxanthin — These carotenoids are vital for good vision and work together to protect your eyes from oxidative stress. Top sources of lutein and zeaxanthin are cantaloupe, corn, carrots, and red and yellow bell peppers.

Selenium

This important antioxidant is actually a mineral and originates in soil, where it’s soaked up by growing plants. Selenium is crucial for reproductive hormones as well as thyroid health. Top food sources include Brazil nuts, brown rice, mushrooms, oatmeal, and spinach.

Zinc

The mineral zinc can work as an antioxidant in the body. However, it also works synergistically with other antioxidants to increase their impact. Zinc is essential for DNA protection, wound healing, and the health and functioning of your immune system. For some people, leading sources of zinc are seafood like oysters, crab, and lobster. But good plant-based sources include nuts, seeds, whole grains, and legumes.

For more on the benefits and risks of zinc, and how much you need, see our article, here.

Polyphenols

Polyphenols are a category of pigments, of which the largest group is called flavonoids. They include subgroups like flavones (luteolin and apigenin), anthocyanidins (malvidin, pelargonidin, peonidin, and cyanidin), flavanones (hesperetin, eriodictyol, and naringenin), and isoflavones (genistein, glycitein, and daidzein). Best known for their disease-protective effects, polyphenols can be found in many different types of plant foods, including fruits, vegetables, whole grains, and legumes. Coffee, tea, and dark chocolate are also popular sources of polyphenols.

Omega-3 Fatty Acids

These polyunsaturated fatty acids come in three main forms: eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and alpha-linolenic acid (ALA). Some plant foods have ALA, but EPA and DHA are found mainly in fish, certain sea vegetables, and algae. The human body can convert ALA to EPA and DHA, though the efficiency of conversion varies from person to person.

Some people are efficient converters and may do just fine if they eat plenty of ALA. Others benefit from a direct form of DHA and EPA — whether from fish, fish oil, or from an algae-based supplement. Popular foods highest in ALA are flax seeds and chia seeds, with moderate amounts in hemp seeds and walnuts.

Omega-3s are beneficial for brain and heart health along with possessing anti-inflammatory and immune-supporting qualities.

For more on omega-3 fatty acids, including the best sources and how much you need, see our article, here.

Are Antioxidant Supplements Worthwhile?

Many antioxidants are available as highly concentrated supplements. So how does that compare to eating them in food directly?

In a 2004 study published in the American Journal of Clinical Nutrition, researchers put some participants on a fruit- and vegetable-heavy diet while giving others a supplement containing the same antioxidant nutrients.

The study leaders concluded that dietary intervention was better than the supplements at combating oxidative stress.

Foods contain a variety of antioxidants that work synergistically, so they tend to be more effective than supplements, which offer nutrients in isolation.

In fact, the majority of studies on antioxidant supplements have concluded that they provide few, if any, significant health benefits.

Risks of Antioxidant Supplements

While I’m not aware of any research that shows problems ensuing from overconsumption of antioxidants from food, it does seem that some antioxidants can be harmful when taken excessively in supplement form. For example:

• Beta-carotene: A 1996 study published in The FASEB Journal found that beta-carotene supplements may actually increase lung cancer incidence in smokers. This conclusion was also confirmed again in a 2019 randomized, double-blind trial among Finnish men.
• Vitamin E: A 2005 meta-analysis published in the journal Annals of Internal Medicine found that taking a daily dose of 200 IU of vitamin E per day did not raise the risk of death and had possible health benefits. However, the researchers found that for those taking daily doses of 400 IU or more, the risk of death was about 10% higher than among those taking placebos.
• Selenium: High levels of selenium supplementation have been linked to type 2 diabetes, high triglycerides, prostate cancer, heart disease, and issues with immune and thyroid function.

Top Antioxidant-Rich Foods

In a 2010 study published in Nutrition Journal, researchers measured the antioxidant concentration of more than 3,100 foods, including everything from nuts and seeds to breakfast cereals and grilled chicken.

Their conclusion? “Antioxidant-rich foods originate from the plant kingdom while meat, fish, and other foods from the animal kingdom are low in antioxidants.”

Here are 12 of the top antioxidant-rich foods and spices; and remember, it’s important to eat organic as much as possible because pesticides can also create free radicals in our bodies:

1. Clove

The study mentioned above ranks clove as one of the foods with the highest antioxidant capacities thanks to its high levels of phenolic compounds. Clove is also known for its antimicrobial and anti-inflammatory capabilities, making it an important food for immunity. While often associated with the holidays, ground clove has a sweet-meets-savory flavor and can be used in desserts, mocktails, soups, and many other flavorful dishes.

2. Pomegranate

Both pomegranate arils and juice have a high antioxidant content due to their flavonols, vitamin C, and the anthocyanins that give them their color. The compounds in pomegranates make for effective free radical scavengers and can reduce oxidative stress. Use the arils in salads and desserts, and the juice in dressings, marinades, and beverages.

For more on pomegranates and their benefits, check out our in-depth article on them.

3. Artichokes

According to the aforementioned Nutrition Journal study, artichokes are among the top antioxidant-rich veggies. But don’t just eat the hearts — the leaves contain a lot of the good stuff, including phytochemicals and flavonols! If you’ve never cooked whole artichokes, it’s easier than it appears. Find out more in our article, Artichokes: Nutrition, Benefits, & How to Cook and Eat Them.

4. Oregano

A great addition to plant-based pizza or almost any savory dish, oregano is big on taste and nutrient density. Research has found it to be a strong antioxidant due to the phenols carvacrol and thymol.

You can easily grow oregano at home in an indoor or outdoor garden, along with other antioxidant-rich herbs, such as rosemary, thyme, and sage. We use it in our Vegan Feta, and it is absolutely delicious!

For more on oregano, see our article, here.

5. Allspice

This versatile spice contains vitamin A, vitamin C, eugenol, quercetin, and tannins. Often used as a folk remedy, allspice has antioxidant properties that are protective against cardiovascular disease, digestive disorders, and obesity. It’s commonly added to sweet dishes and baked goods, or for a more robust flavor, try adding it to stews, curries, and soups. Some people even like it in lasagna sauce!

6. Cinnamon

While not quite as potent as clove, cinnamon is another fragrant spice commonly used in baked goods and other sweets that’s a powerful antioxidant. It’s also known for its specific ability to relax blood vessels, making it a valuable functional food for metabolic disorders. To reap its full benefits, use it with other nutrient-dense foods like oats or legumes.

7. Moringa

While you might expect to see other leafy greens on this list such as kale or collard greens, moringa packs an even more powerful punch. Although not as common as these other leafy greens, moringa is becoming more available either fresh or powdered. It’s a good thing, too, because it’s loaded with polyphenols, carotenoids, and vitamin C. And its capability to fight cell damage also gives it antitumor potential in fighting multiple types of cancer. Include it in smoothies and other beverages, along with soups, stews, and curries.

For more on moringa, read our in-depth article, Meet Moringa: What Is This Transformative Superfood Good For?

8. Blackberries

A 2023 study on blackberries showed they have powerful antioxidant, antimicrobial, and anti-inflammatory activity. It also found they could have applications in both the prevention and treatment of various diseases linked to oxidative stress due to their high levels of anthocyanins, as well as vitamins A and C, carotenoids, and other phytochemicals. You can use blackberries however you use other berries, such as in smoothies and smoothie bowls, salads (including fruit salads), baked goods and other desserts, and mocktails.

If you’re interested in creative ways to enjoy berries, check out our article, 5 Healthy Berry Recipes & How to Use Berries.

9. Sunflower Seeds

Of all the most eaten seeds, sunflower seeds rule them all in terms of antioxidant capacity. Sunflower seeds are high in vitamin E and also contain omega-3 fatty acids, polyphenols, and flavonoids. Although they’re plenty healthy on their own, sprouting the seeds may increase their antioxidant content. You can use sunflower seeds or sprouts in salads, granola, homemade crackers and other snack foods, and in veggie burgers.

10. Dark Chocolate

Chocolate may be responsible for up to 20% of antioxidant consumption in the US and Europe. But when it comes to chocolate, the higher the percentage of cocoa, the better. Dark chocolate has a wealth of antioxidant compounds including polyphenols, flavanols, and catechins. However, if you’re going to eat dark chocolate, you may want to find out the lead and cadmium content as heavy metals have become a concern. You can use chocolate in desserts like nice cream and baked goods, smoothies, overnight oats, or granola.

11. Walnuts

Of all the commonly eaten nuts, when it comes to antioxidants, walnuts reign supreme. In fact, walnuts are one of the plant foods consistently ranked high in terms of antioxidant capacity. They had the highest level of polyphenols out of nine different nuts in one study, and showed potential for inhibiting atherosclerosis and preventing heart disease. Walnuts go well in baked goods, granola, oatmeal; sweet or savory side dishes; and in salads, sauces, and dressings.

12. Coffee

This popular beverage turns out to have loads of antioxidants such as flavonoids and quercetin. In fact, in many different countries, including the US, coffee is the #1 source of antioxidants — by a wide margin. Some researchers even consider caffeine to be an antioxidant, of which coffee also has plenty. Drink coffee straight to get the most bang for your buck. What you put in your coffee matters, as sugar and dairy can have harmful effects on your health and can decrease the coffee’s antioxidant effects.

For more on coffee, check out our in-depth article, here.

Antioxidant Recipes

The healing benefits of antioxidants never cease to amaze us, and what’s even more amazing are all the tasty ways you can consume them daily! Antioxidants are found in both sweet and savory plant-based foods, so no matter which tastes you prefer, we’ve got something for everyone with these antioxidant-rich recipes!

1. Morning Mocha Smoothie

Coffee and chocolate may be two of the most soul-satisfying antioxidant-rich foods on the planet. Featuring them together creates a flavor combination that is simply blissful! Because you get two superfood stars in one scrumptious smoothie, you get tremendous amounts of polyphenols (a potent type of antioxidant). With the addition of bananas, dates, walnuts (which are also rich in antioxidants), and hemp seeds, you get a nutrient-powered smoothie that will surely give you a boost of energy to start the day!

2. Grilled Romaine, Sunflower, and Pomegranate Salad

Nutty sunflower seeds and tart pomegranate are the antioxidant duo you didn’t see coming! Grilled romaine not only puts a new spin on salad, but this recipe also provides an explosion of plant-based antioxidants like vitamin E, omega-3 fatty acids, and polyphenols from the sunflower seeds as well as vitamin C, flavonols, and anthocyanins from the pomegranate. With so many antioxidant-rich ingredients in this simple yet delicious salad, it’s a winner both in nutrition and presentation!

3. Cheesy Artichoke and Asparagus Penne

Artichokes are among the top antioxidant-rich veggies — and boy, oh boy do we love them (and hope you do, too!) in this Cheesy Artichoke and Asparagus Penne! Full of powerful antioxidant properties, phytochemicals, and essential minerals like magnesium, potassium, niacin, and folate, adding artichokes to your diet regularly is a great way to turn down inflammation and turn up healing plant power. What’s more, this colorful pasta is packed with fiber from the veggies, whole grains, and lentils as well as protein from the lentils — so you’ve got the complete package when it comes to this meal.

Here’s What You Can Take Away from This Article

Now that we’ve taken a look at antioxidants, it’s time to eat the rainbow and spice up your daily diet with as many antioxidant foods as you can. They can help protect you from heart disease, cancer, type 2 diabetes, vision loss, and many other health challenges. And they can even help you to feel and look younger!

When it comes to antioxidants, the whole really is greater than the sum of its parts. So feast on a variety of whole plant foods, and your body will thank you for the rest of your life.

Tell us in the comments:

• How does this article change how you think about antioxidants?

• What types of antioxidants do you need more of in your diet?

• What are your favorite antioxidant-rich foods?

Featured Image: iStock.com/YelenaYemchuk

Read Next:

• What Are Flavonoids? And How Are They Good for Your Health?

The post What Are Antioxidants? And What Are the Most Antioxidant-Rich Foods? appeared first on Food Revolution Network.

Well, that’s the experience I just had researching this article about figs. I thought I knew a lot about this yummy fruit until I started digging into the topic. Spoiler alert: They’re not even fruits! And when I discovered how they get pollinated — that’s a drama worthy of a Game of Thrones episode!

But aside from their storied pollination method, figs have a lot to offer. In addition to being a delicious food, figs have also traditionally been used for healing and for some very practical purposes. For countless generations, people around the world have made poultices from fresh or dried figs, fig leaves, and fig wines. Fig stems and leaves contain latex. And, of course, fig leaves have served as, well, strategically placed garments since the Garden of Eden (at least according to some Renaissance painters).

You can also find mention of figs in both the Bible and the Quran. Biblical writers often use figs as metaphors for the physical and spiritual health of the people, with phrases like “everyone under their own vine and under their own fig tree” depicting a time of peace and prosperity. The Quran quotes the prophet Muhammad as telling his followers to eat the fig “as it cures various diseases.”

In this article, we’re going to focus on the culinary uses of figs. We’ll explore what figs are, how they taste (and how they differ from dates), the nutritional value of fresh vs dried, and their health benefits and downsides.

We’ll also look at how they get pollinated (so dramatic!), and if that process might render figs unfit for a vegan diet.

What Are Figs?

Fig trees (or Ficus carica) are native to the Mediterranean region and were one of the first plants to be cultivated.

Figs are members of the mulberry family, which, contrary to the nursery rhyme, is mostly populated by trees, not bushes to “go ‘round and ‘round.” (Other family members include the banyan, breadfruit, jackfruit, and Osage orange.)

A fig fruit (which, again, is not really a fruit) is known as a syconium. According to the Ecological Society of America, “a fig is not actually a fruit; it is an inflorescence — a cluster of many flowers and seeds contained inside a bulbous stem.” And as we’ll see, it’s that structure that makes its pollination so darn interesting.

Because the fig flower is arranged so unusually, the seeds — which are actually the ovaries of the fig — can’t be pollinated by ordinary flying insects like bees, moths, and butterflies. Instead, it requires a pollinator with the skills of a safecracker who can operate in dark, confined quarters (more on that later).

Types of Figs

There are more than 750 different varieties of fig. Some of the types you’re likely to encounter include Adriatic, Black Mission, Turkish/Brown Turkey, Calimyrna, Kadota, Celeste, and Tiger. Different types have different flavor profiles, and feature in a variety of dishes, from sweet desserts to more savory fare.

The most common dried figs in the US are Black Mission and Golden, both of which are grown in California.

Figs are light green as they grow. They may remain green or change color as they ripen, ranging from yellow to brown to dark purple, depending on the cultivar.

The Differences Between Figs and Dates

Figs and dates are two very different foods that people sometimes get confused with one another, kind of like the actors who play Harry Potter and Frodo. Here are some key differences. Frodo didn’t go to Hogwarts — oops, I mean, here are some key differences between figs and dates.

While figs originated in the Mediterranean region, dates are native to several geographical locations, including North America. Figs grow on trees, while dates are the fruits of palm trees, which are technically grasses and not trees (this is such a genus-bending article!).

Furthermore, figs grow on fig tree branches, while dates grow in clusters on offshoots from the main trunk of the palm tree. Dates contain a single pit, while figs have many small edible seeds.

When it comes to eating the fruits, they’re also quite different. Figs have three times the amount of water as dates, which also makes them much lower in calories (about four times lower, if you’re counting). So dates are a much more concentrated source of carbohydrates, mostly in the form of simple sugars. Dates are also richer sources of some minerals, such as calcium and potassium.

Nutrients in Figs

The good news is figs deliver a lot of essential nutrients. The predominant macronutrient (the one that provides calories) is carbohydrates, but they’re also rich in some vitamins and organic acids. As whole plant foods, they also provide important dietary fiber.

According to the US National Nutrient Database, two medium raw figs contain roughly 3 grams of fiber. Doing the math, this means that if you ate just 8 figs a day and nothing else, you’d still get about half as much fiber as the average US resident consumes in a day. (To be clear, I am NOT recommending the “8 Fig a Day Diet,” although someone could probably write a best-selling diet book with that title.)

However, some researchers have measured much greater amounts of fiber in different fig cultivars. According to the American Botanical Council, two fresh or 4–5 dried figs provide a whopping 12 grams of fiber.

So we have credible authorities telling us that two figs provide 3 grams of fiber, while others say the correct figure is 12 grams of fiber. It reminds me of the old saying, “A person with one watch knows what time it is. A person with two watches… is never quite sure.” So for now, let’s just say that figs are high (potentially very high!) in fiber, and leave it to the good folks at the US National Nutrient Database and the American Botanical Council to duke it out on the details.

Figs are a good source of many bioactive phytonutrients, too, including flavonoids, phenolic acids, carotenoids, and tocopherols.

(Here’s a fun article all about flavonoids, which starts with a weird story about a bunch of soldiers trying to cross a bridge.)

They’re also solid sources of potassium, calcium, sodium, magnesium, and phosphorus. What’s more, figs provide essential trace elements, including iron, manganese, zinc, and copper.

You’ll get the most nutrients if you don’t peel your figs; the highest concentrations of phytonutrients are in their skin. And darker fig varieties contain more polyphenols and antioxidant power than lighter ones.

Figs also lose some phytonutrients when dried. Studies show a loss of 29% to as much as 86% of the polyphenol content when figs are dried.

Health Benefits of Figs

In the Middle East and Mediterranean regions, figs have long been revered for their contributions to human health and longevity. The fruit, leaves, latex, bark, and roots of fig trees have been used to treat gastrointestinal, respiratory, inflammatory, and cardiovascular disorders, as well as ulcerative diseases and cancers. The various parts of the fig tree possess a wide variety of properties; they can help you poop, relax muscle spasms, fight viruses and bacteria, bring down high blood sugar, and even help your body expel parasites.

And modern scientific research has only added to our understanding of the power of figs to promote health.

Figs and Gut Health

When patients with irritable bowel syndrome add figs to their diet, they often experience decreased symptom occurrence and severity. A 2019 study gave IBS patients 90 grams of dried figs per day for four months. Compared to controls who didn’t get anything, the fig-enhanced group had reduced frequency of pain, less intestinal distention, more frequent pooping, and softer stools. Unsurprisingly, they also reported “a significant increase in quality of life.”

In a 2018 animal study, rats with induced ulcerative colitis were fed a liquid extract containing figs. The treatment had a natural laxative effect but did not lead to diarrhea, and it improved their gastrointestinal functioning. (Our view on the use of animals in medical research is here.)

Figs and Diabetes

Figs (and fig leaves) can also be deployed to treat diabetes. A 1998 study found that people with type 1 diabetes who drank tea made from fig leaves were able to lower their blood sugar immediately following meals. And a 2019 study showed that a fig leaf decoction was able to lower blood sugar in people with type 2 diabetes by about half as much as the drug metformin (after two months of treatment).

It’s not just the leaves, though — fig fruits contain a compound called abscisic acid (which should definitely be included in spelling bees) that has been shown to reduce blood sugar levels after meals.

Figs and Cognitive Decline

Studies with experimental animals have shown that figs may help us stay sharp and avoid or delay cognitive decline. One animal study compared the effects of a diet that included figs to a fig-free diet in mice that were genetically engineered to develop Alzheimer’s disease. The mice who ate figs did better on memory tests, displayed fewer anxiety behaviors, learned new things more quickly and fully, and had better motor coordination. Furthermore, the fig-eating mice had lower levels of the toxic amyloid beta proteins that are associated with the development of Alzheimer’s disease.

Are Figs Vegan?

This may seem like an odd question, but remember that Game of Thrones reference from earlier? It turns out, fig tree pollination is a bit controversial.

You see, there are two types of fig trees: wild and cultivated. And wild-growing fig trees require pollination to bear fruit. The critters that have volunteered for the job are fig wasps, a term that describes any of several hundred different, mosquito-like tiny creatures from the Agaonidae family. Each species of fig wasp pollinates only one variety of fig.

Basically, here’s how it works.

A female wasp, loaded with pollen, flies to an unripe fig and burrows into its center to deposit her eggs. While she’s doing this, two things happen. One, she spreads her pollen onto the female flowers. And two, the effort of fighting her way through the flower strips her of her wings.

Now the fig goes to work, building structures called galls over the wasp eggs and producing seeds in the flowers that don’t contain the eggs. Meanwhile, the mama wasp dies, whereupon her exoskeleton is dissolved by figgy enzymes. (Cue the emotional orchestral music.)

The heroic male wasps hatch first, and travel around the syconium fertilizing their sisters who are still pupating in their galls. (This is definitely HBO-worthy stuff!) Then they dig holes through which the fertilized females can escape with their wings intact. Once the females hatch, they fly off to repeat the process, leaving the males to die in the maturing fig.

Pretty intense family drama, huh?

As a result, some vegans do not eat figs because they don’t want to consume dead wasps, and also because animals died as part of the process that produced them. However, there’s good news if you want to adhere to a vegan diet and still enjoy delicious figginess.

First, the wasps are completely dissolved by the plant enzymes, so you are not likely to encounter a dead insect in your fig. And second, almost all figs produced and sold in the US are of the cultivated variety and are self-pollinating. This means they don’t need the sacrificial services of the fig wasps, and are considered vegan-friendly.

Fig Downsides

Aside from the fig wasp controversy, there are some other things about figs to consider. For one, some people may have to avoid them because of allergic reactions, including oral allergy syndrome. The latex in the plant may also be a source of irritation and allergy, especially if you’re harvesting figs.

Also dried (but not fresh) figs are high in compounds called salicylates, which may cause swelling, itching, hives, worsened asthma, and food intolerance symptoms in people who are sensitive to them.

The other thing about figs is that it takes a lot of water to grow them. Although they’re not as needy as some other crops like citrus, almonds, alfalfa, and pasture grasses, in places straining under multiyear droughts, such as California and Spain, this can be a problem.

On the other hand, fig trees, like almond trees, are drought tolerant, so they can be a good solution in some cases. While they may not bear fruit during times of drought, they can survive until the rains return. There are several strategies growers can implement, including mulching, thinning fruit to help the remaining fruit develop fully, and protecting trees with shade cloth during the hottest parts of the day.

One other challenge with growing figs, and I say this from personal experience, is that for some reason gophers love their roots. So if you aim to grow a fig tree, it may be wise to place a wire gopher barrier in the planting hole to protect the root ball from those sharp little teeth.

Overall, growing figs appear to be a net positive for the environment. Offsetting their water needs and their moderate carbon footprint, they don’t require heavy use of pesticides. Plus, fig trees sequester carbon in their biomass, keeping it out of the air and not contributing to the climate crisis.

We Dig Figs!

As you’ve probably gathered by now, figs are pretty unique! Their biology is fascinating, and the saga of their pollination is dramatic, to say the least. They also offer a wide range of essential nutrients and health benefits. From their versatile culinary uses to their historical uses as healing agents, figs have proven themselves valuable partners to the humans who have loved, cultivated, and revered them for millennia.

If you’re inspired to add more figgy goodness to your diet, we’ve got you covered: Here’s an article all about different ways of preparing and eating figs.

Tell us in the comments:

• What’s the most surprising fig fact you got from this article?

• Can you find fresh figs where you live? If so, what do you do with them?

• Have you ever planted a fig tree?

Featured Image: iStock.com/SGAPhoto

Read Next:

• Are Dates Good For You, or the Planet?
• Are Grapes Good for You?

The post Figs: Are They Good for You and the Planet? appeared first on Food Revolution Network.

Since then, the search for a fountain of youth has been a recurring obsession of kings and explorers, pilgrims and pirates. As far as I know, none of them ever found it (or if they did, they aren’t sharing any details). No spring, river, pond, lake, or sea has magically rejuvenated the bathers who submerged themselves in its water to the point where creaky elders limp in and dewy-eyed adolescents leap out.

If you’re searching for clues to living a long and healthy life, you probably need to look elsewhere. And a huge factor in the rate of aging turns out to be a class of compounds found in many of our most common (and sadly, most beloved) foods. If you want to slow down your biological clock, limiting your consumption of these foods appears to be a much more reliable and effective strategy than dunking yourself in a mangrove swamp in Bimini or a waterfall pool at the foot of a South Indian mountain.

The compounds are known to biochemists as advanced glycation end-products, which might be hard to remember except for their most excellent acronym: AGEs. As in, AGEs that accumulate in your tissues — make you age faster.

Aging isn’t just a vanity issue that sells stock image licenses to fashion magazines and anti-wrinkle creams to their readers. It’s a big deal for your overall health because, statistically speaking, the single biggest risk factor for disease and death isn’t your genes, or your diet, or how much you exercise, or whether you live downwind of a Superfund site, or whether you drink enough water or put on sunscreen, or any lifestyle or environmental factor; it’s your age.

Which means that because AGEs can contribute to the development of various age-related diseases and conditions, they can shorten your lifespan.

The good news is, you have a lot of control over the amount of AGEs you consume, which in turn largely determines the concentrations of these compounds that accumulate in your body and how much harm they get to perpetrate.

In this article, we’ll dive into the world of AGEs and their impact on your health. We’ll see how your food choices — as well as various cooking methods — can affect the formation of AGEs. And we’ll discover some simple and delicious ways to minimize AGEs in your diet — so you can increase your odds of a longer, healthier, and happier future.

What Are AGEs?

Advanced glycation end-products are harmful compounds that form through a natural process called glycation. It takes place inside your body when the sugars in your bloodstream react with proteins, lipids (fats), and nucleic acids from the food that you eat.

You can also introduce AGEs into your body fully formed, as it were. They form exogenously (that is, outside the body) when foods are browned and their outer layer becomes crispy and crunchy. This chemical reaction is known as the Maillard reaction, or nonenzymatic browning. The Maillard reaction gives foods a texture, taste, color, and aroma that most people find very pleasing.

You can also introduce AGEs into your body through drinking alcohol and smoking.

As you age, AGEs can start to accumulate in your tissues and organs. The more your blood sugar levels fluctuate, the more AGEs form, and the more the effects of glycation intensify and accelerate the aging process.

AGEs can also cross-link with various proteins in your body, leading to the formation of abnormal structures and interfering with the functioning of important molecules. This further contributes to the aging process.

Why Are AGEs Bad for You?

Advanced glycation end-products have been shown to be toxic, immunogenic (triggering an immune response, typically unwanted and over-the-top), and capable of triggering cellular injury. Another remarkably on-point acronym, RAGE, stands for Receptor for Advanced Glycation End-products. It is a receptor protein for AGEs that plays a role in the inflammatory response and has been implicated in various age-related diseases and conditions, including skin damage, respiratory disorders, neurodegenerative diseases like Parkinson’s and Alzheimer’s, cancer, type 2 diabetes, and cardiovascular disease.

Skin Health

AGEs contribute to skin aging, including the formation of wrinkles and brown spots. They affect how proteins work in the dermis (the middle layer of your skin), leading to lots of problems: decreased elasticity, delayed recovery from wounds, accelerated skin aging, and inflammation that can contribute to skin conditions like dermatitis and psoriasis.

Collagen (a type of protein found in our connective tissue, cartilage, bone, and tendons) is one of the structures most easily attacked by AGEs. Over time, AGEs can accumulate on collagen, causing the skin to turn yellow.

Neurodegenerative Diseases

Autopsies of people who died from or with Alzheimer’s disease have shown accumulations of AGEs have been found in their brain plaques, as well as in their blood serum and cerebrospinal fluid. AGEs can also hasten the ravages of Parkinson’s disease by contributing to neuronal cells’ self-destruction as well as the formation of Lewy bodies (structures associated with abnormal deposits of a particular protein in the brain).

Respiratory Disorders

The more AGEs a person consumes, and the more frequently they eat meat, the more likely they are to experience breathing problems. This includes symptoms of asthma in children, such as wheezing. Kids who consume the most AGEs typically need more asthma meds, have their sleep interrupted by wheezing episodes, and are most limited in their ability to exercise without shortness of breath.

When COVID-19 hit, many of the initial deaths were linked to an immune system overreaction known as a cytokine storm. AGE consumption appears to be linked to worsening outcomes in COVID patients due to more extensive lung damage. AGEs also can lead to severe pneumonitis (inflammation of the lung tissue) by impairing the immune response, triggering inflammation, changing the structure of lung tissue in a way that decreases lung function, and enabling bacteria to adhere more easily to the lungs.

Type 2 Diabetes

The AGEs that are created by cooking certain foods in certain ways (known as exogenous AGEs, to differentiate them from the endogenous AGEs that are synthesized inside our bodies) can be extremely harmful to people with type 2 diabetes. In addition to adding to the inflammation that can trigger the development of the disease, AGEs also contribute to diabetic retinopathy and other related issues that can damage eyesight.

Some of the vascular dysfunction associated with diabetes can be prevented by blocking the RAGE receptors. And proactively consuming a diet low in AGEs can increase insulin sensitivity, which can reduce the risk of developing type 2 diabetes in the first place.

Cancer

With cancer, AGEs can act like gasoline thrown on a fire, increasing carcinogenic processes in a wide range of cancers and promoting their malignant behaviors. A 2015 study of male members of the US-based AARP found that the more AGEs they consumed, the greater their risk of developing pancreatic cancer. And a 2022 study of over 14,000 Japanese men found that high AGE intake was significantly associated with an increased risk of liver cancer.

AGE-Forming Foods

I hope by now you’re motivated to find out where these AGEs are hiding, so you can consume as little of them as possible. So here are the five main categories of AGE-forming foods.

Meat

In the standard industrialized diet, meat is typically the largest contributor to AGE formation. They’re created when the proteins in meat get a little too friendly with sugars, particularly glucose and fructose, that can be added during processing (some examples are many forms of bacon, hot dogs, and corned beef) or via marinades.

When meat is cooked at high temperatures, especially over an open flame or on a grill, it can produce harmful compounds that contribute to AGE formation. Some of the worst offenders are heterocyclic amines (HCAs) and polycyclic aromatic hydrocarbons (PAHs), which are classified as potential and known carcinogens, respectively.

Regardless of the cooking method, any blackened or charred meat will contain these compounds. The levels depend on the type of meat (beef is worst), cooking conditions, and final internal temperature.

If you’re wondering why humans tend to love the color, smell, texture, and taste of something that’s so bad for us, it’s probably because the Maillard reaction is a good indicator that the meat has been cooked enough to kill the pathogens that could kill you. From an evolutionary perspective, the AGEs that keep us from reaching old age are far preferable to the germs that could end your life in the next few hours or days.

Fried Foods

Frying and other high-heat cooking methods also increase the AGEs in foods. A big culprit here is the repeated heating and use of cooking oil in commercial settings. That oil accumulates large amounts of AGEs, which get transferred to those fries or mozzarella sticks when they’re submerged in their fryer basket.

The longer the food is exposed to high-temperature frying, the more opportunity there is for the Maillard reaction and AGE formation to occur. Even changing the cooking oil daily leaves room for lots of AGEs. Swapping out large containers of hot oil is a dangerous and not very fun job, so some restaurants or commercial kitchens schedule the task only every few days. (I asked a friend’s son who once worked in a local restaurant how often they changed their cooking oil, and he responded, puzzled, “I have no idea if they ever do.” Sometimes I’d rather not know certain things.)

Cheese

The highest concentrations of AGEs are found in aged and hard cheeses in particular, probably because they’re pasteurized and/or they spend a lot of time aging or curing at room temperature — conditions that make up a veritable AGE factory. But all dairy cheeses are potential sources of AGEs, perhaps because dairy contains large amounts of fat along with natural lactose sugar.

Processed and Packaged Foods

Processed and packaged foods are often high in AGEs. Many of them contain added sugars, and undergo high-temperature processing as they’re baked or fried. They’re high in AGEs via that good old Maillard reaction, which is responsible for the browning and flavor development in cooked foods, and which can also extend shelf life.

Sugary Foods

Since AGEs form via glycation (essentially, sugarcoating proteins and fats), foods high in added sugars, such as candies, pastries, and sugary beverages, can provide fodder for the glycation process and contribute to the formation of AGEs.

There’s data that suggests that the glycation process following high sugar intake may be a key player in the development of metabolic disturbances.

Foods and beverages with a high fructose-to-glucose ratio may promote AGE formation. These can include anything with high-fructose corn syrup, agave nectar, honey, and filtered fruit juices. A glaring exception to this rule is fruit, which is actually protective against AGE-related disease thanks to its high fiber content.

Especially worrisome are commercial soft drinks sweetened with high-fructose corn syrup, which are often high in an intermediate product of the Maillard reaction called methylglyoxal.

Why Eating a Whole Food Plant-Based Diet Is the Best Way to Avoid AGEs

You can’t avoid AGEs entirely — pretty much every food contains some. But whole plant-based foods, including fruits, vegetables, whole grains, legumes, nuts, seeds, and herbs and spices, naturally have lower levels of AGEs than animal-derived foods. And some cooking methods commonly used on plant foods — steaming, boiling, and baking — produce fewer AGEs than the higher-temperature methods like frying, grilling, and broiling that are commonly used for foods of animal origin.

It’s definitely possible to get exposed to significant quantities of AGEs on a plant-based diet if you routinely fry starchy foods like potatoes (I’m looking at you, potato chips and french fries!). These foods also produce acrylamide, another compound that may be problematic for some people when consumed in large quantities.

But even when fried or broiled until brown and crispy, most whole plant-based foods offer compounds that can mitigate the damage caused by AGEs. Many are rich in antioxidants, such as vitamins C and E, the provitamin beta-carotene that your body converts to vitamin A as needed, and various phytochemicals that help neutralize the free radicals that can contribute to AGE formation and oxidative stress in the body.

Also, the soluble fiber available from plants helps regulate blood sugar levels and can reduce the glycation process by slowing down the absorption of sugars in the bloodstream.

5 Foods (and 1 Beverage) That Prevent Glycation

You can go a long way toward reducing AGEs and RAGE in your body by avoiding or limiting highly processed foods and those of animal origin, and by using lower-temperature cooking methods that don’t produce crispy, crusty browning on the outside.

In addition to those strategies, you can also consume some specific foods that contain compounds that inhibit the glycation process, so that the AGEs you do inevitably consume have less risk of causing aging and accompanying health problems.

Berries

The antioxidants in berries help reduce the conditions that lead to glycation by scavenging and neutralizing free radicals. Polyphenols found in berries, especially anthocyanins and quercetin, may directly inhibit the formation of AGEs. And extracts made from the skins of red grapes (which are, botanically speaking, berries) were able to inhibit the creation of AGEs in a test tube containing fructose-glycated proteins.

Berries also deliver anti-inflammatory and blood sugar-balancing effects.

For more on berries and some “berry” great recipes, see our article here.

Spices

Many spices, some commonly used in modern kitchens and some still awaiting their turn as superfood du jour, have been shown to prevent AGE formation through their powerful antioxidant activity. Examples include star anise, cinnamon, allspice, and cloves, which are staples in many traditional cuisines around the world. And good old black pepper also performed well at this task.

Other powerful anti-AGE spices include garlic and turmeric which contains the powerful antioxidant curcumin.

For more on herbs and spices, see our article here.

Nuts

Nuts, led by walnuts and pistachios, are great at inhibiting the glycation process in early and intermediate stages, before they even have a chance to reach the end stage indicated by “AGEs.” They are also powerful anti-inflammatories, helping to prevent damage related to any glycation that still occurs. Additionally, nuts have high antioxidant capacity (thanks to their concentrations of vitamin E) and are rich in phenolics and flavonoids that fight free radicals.

For more on nuts, see our article here.

Cruciferous Vegetables

Cruciferous vegetables contain the powerhouse antioxidant and anti-inflammatory sulforaphane, which is famous not just for giving cabbage and broccoli their distinctive odors, but also for being one of the most effective cancer fighters ever identified.

One of the ways sulforaphane delivers its massive health benefits is by inhibiting AGE-induced damage. In this way, it may prevent cardiovascular and diabetes-related complications. Broccoli sprouts, in particular, may play a protective role against vascular injury by inhibiting the AGEs’ (and their receptors’) axes and exhibiting anti-inflammatory actions.

For more information about sulforaphane and how to get it into your diet even if you aren’t a cabbage fan, check out our comprehensive article here.

Citrus

Perhaps the OG antioxidant, and certainly the one with the most publicity, vitamin C lives up to its reputation by helping to inhibit glycation processes. When researchers marinated lean beef in lemon juice for an hour before cooking, it ended up with half the AGEs as the same cut of beef marinated in vinegar.

It’s not just the vitamin C in citrus foods that deserves the credit. Flavonoids such as hesperidin, naringin, and quercetin have anti-inflammatory effects and help reduce the conditions that promote glycation. Hesperidin in particular is being studied for its potential to treat glycation-induced neurotoxicity involved in Alzheimer’s disease.

Citrus fruits also support healthy endothelial function. The endothelium, a layer of cells that lines your blood vessels, can contribute to the development of AGEs when it isn’t working properly, so the support of compounds in citrus fruits can go a long way in keeping glycation in check.

For more on the health benefits of oranges, see our article here.

Green Tea

There’s a compound found in green tea called epigallocatechin 3-gallate, which goes by its fun acronym EGCG, which sounds like the name of a trendy dance club from the 1980s (there may be an alternate universe in the multiverse in which I know very little about nutrition and a great deal about house music). EGCG helps protect proteins and other molecules from glycation by neutralizing free radicals before they have the chance to party and form AGEs. In this way, green tea consumption may help prevent neurodegenerative disease.

Through the same pathways, EGCG may also reduce plasma glucose and alleviate complications of diabetes.

For more on the health benefits of teas, see our article here.

Recipes to Fight Aging from AGEs

Defending yourself against the rapid formation of AGEs can feel like a mighty task, but with these nourishing recipes, it couldn’t be more simple. These recipes have powerful anti-inflammatory ingredients that actually counteract the damage that AGEs can do to your tissues. So grab your favorite kitchen knife and cutting board and get ready to unlock a world of fresh, wholesome, and nutritious plant power!

1. Strawberry Pistachio Iced Matcha Latte

Matcha, strawberries, and pistachios offer triple the anti-inflammatory support to stop AGEs in their tracks! Keep your skin, hair, nails (and everything in between) looking youthful, healthy, and vibrant with this creamy, fruity, and naturally sweet latte!

2. Summer Citrus Salad

This Summer Citrus Salad is as refreshing as it sounds. Juicy grapefruit, sweet oranges, floral blackberries, and earthy spinach are tossed in bright and zesty lemon juice. Together, these tantalizing plants offer a potent dose of vitamin C, beta-carotene, and powerhouse antioxidant and anti-inflammatory compound sulforaphane. This salad is not only mouthwateringly nutritious, but it’s a great way to neutralize free radicals and prevent AGE formation and oxidative stress in the body. If that is not enough to convince you to give it a try, the aroma of the freshly segmented orange and grapefruit is simply delightful!

3. One-Pot Curry Cauliflower Chickpea Chili

One-Pot Curry Cauliflower Chickpea Chili offers a sweet and savory flavor profile with the addition of cinnamon and turmeric. Loaded with antioxidant and anti-inflammatory properties from both of the spices, and plenty of sulforaphane from the cauliflower, this Indian-inspired chili has an abundance of AGE-fighting plant power in every bite!

AGEs can Age You!

AGEs contribute to a number of health conditions, from skin aging and respiratory disorders to neurodegenerative diseases and cancer. Although AGEs occur naturally as you age, and are found in food and produced in your body, you do have a lot of control over how much you’re exposed to them through diet. By avoiding AGE-forming foods such as animal products and processed foods, you can minimize your intake and protect your body from further harm. You can also reduce your exposure by embracing healthier cooking methods, reducing or eliminating added sugars, and choosing antioxidant-rich plant foods like berries, spices, nuts, cruciferous vegetables, citrus fruits, and green tea.

Tell us in the comments:

• What are some foods that you’ve cut back on or eliminated for health reasons?
• What foods that counteract glycation do you regularly eat?
• What’s one anti-AGE food that you can begin to add to your diet?

Featured Image: iStock.com/frantic00

Read Next:

• How to Avoid Temptation & Slay the Sugary Beast

The post What Are AGEs & How Do You Avoid Them in Food? appeared first on Food Revolution Network.

Have you noticed a lot of CBD talk in recent years? Or that you can suddenly find it almost everywhere? Well, that’s because, in 2018, the Farm Bill legalized the regulated production of hemp in the United States. When this bill was signed into law, it granted hemp manufacturers the right to mass-produce, sell, and transport hemp and hemp products — and for you to be able to possess and use it.

There was, however, one catch.

Hemp is the same plant species as marijuana, which contains the psychoactive cannabinoid known as delta-9-tetrahydrocannabinol (THC). And so, if hemp producers want to be within the legality of the Farm Bill, their products need to contain less than 0.3% THC.

This bill has had major implications for the natural health world. See, while THC produces the “high” associated with marijuana, there are loads of other cannabinoids within hemp that have been shown to be highly beneficial for human health without causing any psychoactive effects.

The 2018 Farm Bill — along with other more recent legislation — has opened up a whole new area of research into these cannabinoids. Previously, it was difficult to study beneficial cannabinoids due to the restrictions on hemp. So studies were few and far between. But now, scientists are finding out what some had suspected about certain cannabinoids all along — they appear to have extraordinary benefits for human health.

While there are numerous beneficial cannabinoids, in this blog, I want to talk specifically about one that has the most scientific research behind it: cannabidiol (CBD).

Not sure what CBD is — or why you should care about it? Well, keep reading! I’ll go over how CBD interacts with your body to support good health, its legality, types of CBD, and the best ways to take it.

CBD and the Endocannabinoid System (ECS)

Most people don’t realize that their bodies actually create cannabinoids on their own, contributing to a system within the body made up of molecules and receptors. Discovered only in 1988, researchers call this system the endocannabinoid system, or ECS for short.

With cannabinoids, along with their receptors, the ECS helps maintain a certain balance — or homeostasis — within the body, regulating functions related to pain, memory, appetite, and sleep, among others.

When a disruption in ECS homeostasis occurs, it’s known as an endocannabinoid deficiency. This is a situation where the body does not have enough naturally-made cannabinoids to attach to cannabinoid receptors. A deficiency in cannabinoids can throw the body out of balance and cause mismanagement of the ECS’s important functions.

However, a nonpsychoactive compound found within the hemp plant, CBD, can interact with the cannabinoid receptors within your body in astonishing ways. If you’re low in cannabinoids, think of CBD as supplementing these important compounds — enabling your body to find balance once again.

Plus, not only is CBD considered a multipurpose cannabinoid that can interact with many different receptors, it may increase the lifespan and amount of your body’s endocannabinoids, allowing your body to use more of what it’s already naturally producing.

By helping the ECS and supporting various other mechanisms throughout the body, (which you’ll learn about below), CBD may contribute to some remarkable health benefits.

So, without further ado, let’s learn about how this potent natural compound might be able to support your health!

1. CBD Sleep Benefits

If you have sleep issues, or if you just occasionally find yourself having a difficult time falling and staying asleep, consider adding CBD to your nightly regimen. There’s scientific research to back up the use of CBD as a support for relaxing and getting quality sleep.

When we’re stressed, our bodies produce a hormone called cortisol. Dubbed “the stress hormone,” cortisol can negatively impact sleeping patterns. But according to research, CBD could help regulate cortisol levels, helping us to relax.

In fact, a large case series from 2019 found that CBD use improved sleep in participants by nearly 67% after just one month.

And a 2023 systematic review of 34 studies showed that CBD alone (or in tandem with certain forms of THC) might improve symptoms of insomnia.

2. CBD and Joint Health

CBD has also been shown to help ease achy joints and promote a healthy inflammatory response. This is particularly important if you have a condition that causes discomfort within your joints.

For one thing, CBD has been shown to potentially increase the levels of anandamide in our bodies — a neurotransmitter associated with reducing pain perception and improving mood. And a 2021 study found that while CBD isolate oil didn’t reduce the volume of pain, it did make pain less bothersome.

And CBD doesn’t just make things feel better — it can also make them get better by helping manage the body’s response to inflammation. Research shows that CBD may reduce the levels of pro-inflammatory cells in the body while increasing the levels and effectiveness of crucial immune cells.

CBD has also been found to target the areas of the joints suffering from chronic inflammation in people with rheumatoid arthritis, potentially providing relief from uncomfortable symptoms.

And if all of that wasn’t enough, CBD might also help strengthen joint tissue. An analysis of CBD joint studies concluded that there is sufficient evidence that CBD may be able to both reduce cartilage degradation and facilitate cartilage repair.

3. CBD Brain Benefits

Cannabinoid receptors are dispersed throughout many brain regions and are responsible for regulating numerous aspects of activity within your brain.

As such, ongoing research is showing that CBD may have neuroprotective properties, specifically against cognitive decline and certain conditions and disorders of the brain.

One of the main factors in cognitive decline has to do with oxidative stress and inflammation. These states cause damage to neurons, inhibiting proper brain function. But CBD has been shown to offer potentially protective effects in the brain by reducing these factors.

A review from 2021 showed that CBD might be able to both repair and replace neurons, supporting cognition and brain health.

4. CBD and Mental Health

One of the causes of anxiety and depression is certain chemical reactions in the brain. It turns out that CBD may be able to reduce these symptoms by regulating chemicals in the brain.

For example, CBD has been shown to potentially help increase levels of what’s been dubbed the “bliss molecule” — a neurotransmitter called anandamide.

Researchers believe that a deficiency in endocannabinoids such as anandamide can lead to depression, migraines, and other conditions of the brain and nervous system. They also theorize that endocannabinoids like anandamide might offer protection against conditions like anxiety and depression.

It’s also thought that anandamide could help better regulate the body’s stress response.

And there’s another neurotransmitter CBD can influence — serotonin, a chemical that controls mood and makes you feel happy. Low levels of serotonin are linked to depression, anxiety, and mania associated with bipolar disorder. Though CBD isn’t thought to necessarily increase serotonin levels, it appears to change how your body uses the serotonin it does have, activating it and allowing it to better bind to serotonin receptors.

5. CBD and PMS

Chances are that you either know someone who gets menstrual cramps or you get them yourself. These types of cramps are quite common, with approximately 75% of menstruating people experiencing cramps during their periods.

Because of its natural ability to potentially alleviate discomfort and help manage the body’s inflammatory response, CBD is becoming increasingly popular to help relieve menstrual cramps.

A recent review of studies found CBD could be helpful in providing relief for many of the symptoms involved with PMS. Additionally, some researchers theorize that the main cause of menstrual pain — along with many other PMS symptoms — has to do with inflammation. CBD’s ability to affect the body’s inflammatory response is well documented. As such, it may help provide PMS relief by managing inflammation.

6. CBD and Hair Growth

While research is limited in this area, there are some interesting findings that show CBD intake might be able to contribute to increased hair growth.

Once again, it comes back to the ECS. Certain cannabinoid receptors have been found to be key players in hair follicle growth. As such, CBD may be able to help regulate the health of hair follicles.

Additionally, it may help regulate hormones which are often involved in hair loss conditions.

More research is needed, but it stands to reason that CBD might be helpful.

Is CBD Actually Legal?

Okay, so now you may be thinking, these benefits sound great — but I’m still worried about the legality of CBD.

Maybe a coworker told you that CBD isn’t legal everywhere, or you read somewhere that the lines are a bit blurry when it comes to what’s allowed and what isn’t. After all, you don’t want to get in trouble with the law, even if the health results from CBD are promising.

So, is CBD fully legal in the United States — or whatever country you live in?

Well, the fact of the matter is that it depends on where you live. In the US, as in many other countries around the world, there are both federal and state regulations on CBD use, as well as all other forms of the plant that CBD is extracted from — and they don’t always agree with one another. So it’s important to familiarize yourself with local as well as national laws concerning CBD.

Why is the issue of CBD legality complicated? It comes down to both how CBD is grown and extracted.

THC Levels and CBD Legality

CBD comes from a plant species called Cannabis sativa. Plants in this family include cannabis and hemp, which most people consider “sister plants.” The main difference between the two is that cannabis contains more THC — the cannabinoid responsible for the “high” feeling people get from marijuana — and hemp contains more CBD. Even so, some legislators worry that even hemp-derived CBD contains the illegal compound THC. This is why the 2018 Farm Bill clarified that hemp is only legal to produce if it contains less than 0.3% THC.

Essentially, CBD is legal in every state in the US, as well as Washington, DC. But many states have conditions.

While there are a number of states that have zero restrictions on CBD, just as many have certain conditions that need to be met if you want to purchase and use CBD. The main stipulation is that the THC level within the hemp plant the CBD was derived from needs to be at a certain percentage. Following the federal guideline, most are set at 0.03%. But some states allow zero traces of THC whatsoever.

Other states allow up to 0.05% THC, but you’ll need a medical license. And some don’t care about the percentage as long as the CBD is derived from hemp. Other states, like Mississippi, are a bit stricter and require you not just to have a medical license but to obtain CBD only from the University of Mississippi.

So, as you can see, it’s hard to say just yes or no to the question of whether CBD is legal within the United States. And other countries have their own rules and regulations, too.

CBD Types

So if you are able to obtain CBD legally, how do you know what kind to take?

There are many different methods that companies use to isolate and extract CBD and a range of ingredients they choose to add or leave in their products. In addition, there are also different blends that leave or take out flavonoids and cannabinoids. Some even completely isolate CBD on its own.

There are three main kinds of CBD products: CBD isolate, full-spectrum CBD, and broad-spectrum CBD.

CBD Isolate

CBD isolate is just that — pure CBD by itself without any other cannabinoids in the mix. Some people prefer it because it lacks any THC whatsoever. However, isolating CBD from all other cannabinoids requires the most lab processing of the three categories.

Isolate has similar health benefits to full- and broad-spectrum CBD, but lacks the so-called “entourage effect” that occurs with the presence of multiple endocannabinoids and related compounds.

Full-Spectrum CBD

Full-spectrum blends tend to increase in positive effects as the dosage is increased. However, while full-spectrum CBD must contain less than 0.3% THC, it may include trace amounts of THC, the active cannabinoid in marijuana products. Even though the amount of THC found in full-spectrum blends is generally too low to create a “high,” it does have the potential to show up as a positive on drug tests.

For some people, this is a deal-breaker. As we’ve seen, not all states allow CBD with THC above a certain level, or they require a medical card. And some people are also extremely sensitive to THC’s effects and don’t find it to be a positive experience even in tiny amounts.

Broad-Spectrum CBD

Finally, we come to broad-spectrum CBD blends. Broad-spectrum CBD means that all or some of the cannabinoids in the plant are extracted for the blend, minus THC.

My favorite broad-spectrum CBD products are processed in a way that retains all of the cannabinoids’ active properties. And there are quite a few cannabinoids besides CBD and THC (none of which are psychoactive, of course).

Another great thing about broad-spectrum CBD is it is less costly on average than full-spectrum products because the THC is left out. And it’s less heavily processed than CBD isolate.

What Type of CBD Is Best?

Ultimately, it depends on the person. Everyone’s bodies interact with CBD products differently. You may want to try out a few and choose the product that works best for you.

Are There Any Downsides to CBD?

As of the date of this article’s publication, the FDA “has not approved a marketing application for cannabis for the treatment of any disease or condition.” But a few cannabis-derived drugs have been approved.

However, since CBD (as with many supplements) is not regulated by the FDA in anything like the manner that pharmaceuticals are regulated, you may want to research the company and its production methods before purchasing. Some companies cut corners and use treatment and extraction processes that damage the purity and quality of their products, rendering them less effective than they could be — or worse, completely ineffective!

They could also contain unwanted contaminants such as pesticides, bacteria, and heavy metals. According to a report published by the CBD resource site Leafreport, 25% of the 136 brands they looked at did not conduct purity testing for their CBD products.

CBD can also potentially interact with certain medications, including anticonvulsants, sedative drugs, herbal supplements, and narcotics. Side effects can also sometimes occur, especially in high doses, and may include diarrhea, fatigue, vomiting, and drowsiness. I recommend consulting a medical professional before beginning a regular CBD regimen.

How Much CBD Should You Take?

While up to 1,500mg per day of CBD is seen as the tolerable upper limit for consumption, recommended amounts are usually much less.

Various factors may influence dosage amount, including body weight, the condition being treated, type of CBD, and sensitivity. When starting CBD, you’ll likely want to begin with a low dosage, which you can gradually increase as necessary. It may take some time and experimentation to find the right amount, as well as the right type of CBD product for you.

In the book CBD: A Patient’s Guide to Medicinal Cannabis by Leonard Leinow and Juliana Birnbaum, they break CBD dosage down into three categories: micro, standard, and macro.

• Microdose: 0.5mg–20mg of CBD per day
• Standard dose: 10mg–100mg of CBD per day
• Macrodose: between 50mg–800mg of CBD per day

Determining your dosage will also depend on the method you choose to take CBD, so let’s take a look at the types of CBD products that are available.

How to Take CBD

Now that we’ve covered the ins and outs of CBD, including its potential health benefits, you may be wondering how to take it.

There are many different CBD products, and the way in which they’re taken can affect the benefits you get, how quickly it works, and more. Determining what’s best for you may take a bit of experimentation. But as you’ll see, some are more reliable than others if you’re looking to get the maximum benefits out of your CBD usage.

CBD Edibles

CBD through edibles is a fun and easy way to consume the compound. You can do this through gummies, sweets, and even mints. Some food and beverage companies also make CBD-infused products.

Though easy to consume, there are some downsides. Some gummies may be made with gelatin, which could come from factory-farmed animals, and food and beverage products may also include natural and artificial flavorings and sweeteners.

Eating CBD also subjects the compound to something called the “first pass effect.” During this process, CBD is broken down by the liver and digestive tract. As a result, it can take several hours for the CBD to take effect, and you’ll likely only absorb 20–30% of it.

CBD Topicals

CBD topicals are meant to be applied directly to the skin. These can include lotions, creams, balms, ointments, and transdermal patches. This can be a great option for treating skin conditions or inflammation over specific areas of the body.

One study done on rats found that topical CBD greatly reduced joint swelling in the applied area, giving promise to those with arthritis.

However, skin can be hard for these compounds to penetrate. If you do go this route, it’s probably best to use a generous amount of a topical product that has a high concentration of CBD.

Vaping or Smoking CBD

You can smoke CBD in a joint, much like marijuana, use a vaporizer that has CBD oil in a cartridge, or inhale CBD concentrates using a vape pen.

With this method, the CBD hits your bloodstream much faster, and you will likely feel the effects rather quickly. Even then, only about 34–56% of the CBD will be absorbed.

However, taking CBD in this way, as with other smoke products, can also potentially expose you to harmful carcinogens. And research is still underway on the lasting effects of vaping. Based on a growing body of concern about the health effects of smoking and vaping, it seems that it may well be best to avoid this method.

CBD Tincture Oil

This is one of the simplest ways to take CBD. With CBD tinctures or sprays, you drop or squirt the CBD oil into your mouth and swallow. Like other herbal products delivered in this manner, you’ll want to hold the CBD beneath your tongue for a few moments, as the CBD can penetrate the thin tissue if allowed to linger.

CBD oil is a great way to get pure, high-quality CBD in a way that doesn’t have any risks like smoking or vaping.

However, because of its poor solubility, CBD taken this way isn’t absorbed very well, with some reports showing only a 13–19% absorption rate.

Liposomal CBD

Liposomes are membranous, fluid-filled sacs that can help in the delivery of cellular products. They occur naturally in the body, but may also be created synthetically. They’ve been shown to be extremely effective in delivering everything from vitamins to pharmaceuticals safely throughout the body.

Liposomal CBD facilitates survival in the acidic environment of the stomach and absorbs through the intestinal wall.

One study compared liposomal CBD with non-liposomal CBD. They gave the first group of participants standard, orally-administered non-liposomal CBD oil and the second group orally-administered liposomal CBD oil.

After one hour, the non-liposomal group only had 6 out of 15 participants showing CBD in the blood, while the entire liposomal group showed CBD in their blood.

On top of that, CBD levels were significantly higher in the liposomal group. The highest concentration of CBD detected at one hour was 5.9 ng/mL in the liposomal CBD group compared to a mere 1.3 ng/mL in the non-liposomal group. That’s nearly five times as much!

CBD Is a Promising Substance for Your Health

As you can see, CBD has a number of useful applications for your health, especially if you’re somebody already struggling with an issue like insomnia or joint pain, or are worried about cognitive decline.

Because there are different types, methods of consumption, and dosages, you may have to experiment a bit in finding what’s right for you. And it may be wise to work with a health care provider to avoid side effects and any potential medication interactions.

I don’t know about you, but with the increasing availability of CBD and research on its potential uses, I’m excited to see how it continues to help people with a variety of medical conditions.

Even though more research is clearly needed before we know all the pros, cons, and long-term effects of the different forms of CBD, many people are concluding that they’ve seen enough to want to give CBD a try and see how it works in their bodies.

Tell us in the comments:

• Have you heard of CBD or tried it yourself?
• Have you seen results with specific CBD products?
• What other questions do you have about CBD consumption?

Featured Image: iStock.com/ArtistGNDphotography

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The post Is CBD Good For You? CBD Health Benefits, Varieties, & Best Practices appeared first on Food Revolution Network.

If so, you might be a plant-based eater. Or (are you sitting down right now?) you might instead adhere to quite the opposite: a carnivore diet.

Carnivore diets — and yes, there are several — have surged in popularity in the last few years. Starting on the far fringe of nutrition and wellness, the carnivore movement has burst more into the mainstream through books by doctors, publicity on podcasts, and testimonials from popular wellness influencers and online personalities.

While low-carb diets are nothing new (Atkins, South Beach, and keto are all examples), carnivore diets take this trend to a whole new level. Instead of just low-carb, many of them are “zero-carb,” promoting the exclusive consumption of animal-derived foods while shunning most (or all) plants.

Carnivore diet advocates claim that eating nothing but animals is the optimal way for humans to eat. They believe that by doing so, you can achieve your ideal weight, grow big muscles, alleviate autoimmune disease, cure brain fog, and improve your digestion. And if the diet seems extremely limiting, don’t worry; advocates believe you can still get every nutrient you need from animal products alone.

So in this article, let’s explore if there is any scientific basis for these carnivore claims. And while we’re at it, we’ll also look at the diet’s environmental impact. Rather than fan the flames of this particular culture war, let’s separate fact from fiction to make well-informed decisions about our nutritional paths.

What Is a Carnivore Diet?

A carnivore diet means getting the vast majority (or all) of your calories from animal products. A typical carnivore menu includes red meat, game meat, fish, poultry, and organ meat. Some versions also include dairy and eggs, or small amounts of low-starch vegetables like avocados and cucumbers, while others do not. The diets are either extremely low-carb or often no-carb, which means, by definition, excluding all or most plant-based foods.

Carnivore diets are similar to certain forms of keto (ketogenic) and Paleo (Paleolithic) diets, which are often meat-heavy and plant-poor, but carnivore dieters go an extra step. Instead of meat being the centerpiece of every meal, it’s basically the only piece. This puts eaters into ketosis, the body’s “emergency state” that allows it to convert stored fat (and, in extreme cases, protein) into ketone bodies that can be used for fuel when the body’s preferred fuel, carbohydrates, isn’t available.

But for die-hard carnivores, avoiding plants isn’t just about achieving ketosis. There’s also an avoidance of plants because of “antinutrients,” a refrain also seen with Dr. Steven Gundry’s warnings against lectins.

Proponents of carnivore diets make the case that animal products are easier to digest than plants. Asking followers to “[T]hink about it from a plants [sic] point of view,” Dr. Paul Saladino claims that since plants can’t run away or fight back, they create their own pesticides to deter over-predation. And so animals like us experience compromised health because those compounds mess with our digestion, preventing us from absorbing some nutrients and causing intestinal and immune distress.

But in reality, many animals do eat plants (and thrive off them). And many of the antinutrients in plants have profound health benefits and are mostly eliminated anyway during cooking.

We’ll see in a bit if the facts support or contradict this dietary approach. First, though, let’s go deeper into the weeds — or the organs, if we’re relying on flesh-based metaphors here — to explore the prominent subtypes of carnivore diet you’re likely to encounter.

Carnivore Diet Subtypes

The Carnivore Diet

The “standard issue” Carnivore Diet was popularized by Shawn Baker, a former orthopedic surgeon and diet influencer. Baker had his medical license revoked in 2017 by the New Mexico Medical Board for ethical violations and “incompetence to practice as a licensee.” (To some of his fans this only proves that Baker is a truth-teller fighting a corrupt system.)

Baker’s version of the diet allows the consumption of only meat, fish, and other animal products like eggs and certain dairy products.

The Ancestral Diet

The Ancestral Diet is similar to the Paleo diet but prioritizes meat over all other foods. In a nod to reality, it includes seasonal fruits and vegetables in small amounts. It also allows some dairy and fermented foods. Ancestral Diet adherents characterize it as more than just a diet; they see it as a comprehensive philosophy of living that includes a return to nature.

Pros of the Ancestral Diet include avoidance of processed foods and inclusion, although limited, of some plant-based foods.

The Lion Diet

The Lion Diet is where carnivore meets elimination diets. Those on a Lion Diet limit themselves to beef, salt, and water. It got a lot of press when Mikhaila Peterson, daughter of best-selling Canadian psychologist Jordan Peterson, promoted it as a cure for depression, rheumatoid arthritis, muscle weakness, night sweats, asthma, insomnia, PTSD… and a whole lot more. Jordan Peterson adopted the diet as well, and promoted it on The Joe Rogan Experience podcast and his own popular YouTube channel.

The Nose-to-Tail Diet

The Nose-to-Tail Diet has been popularized by Dr. Paul Saladino and Brian Johnson, an online influencer known as the “Liver King” due to his propensity to consume raw liver on the regular. The muscle-bound Johnson has nothing but scorn for most modern men, whom he accuses of being submissive, sub-primal, and weak. They have been brainwashed to eat vegetables rather than dominate, kill, and eat other species, he argues, and so lead mediocre and unsatisfying lives.

Theories of human development aside, this diet consists of eating all parts of the animal, including organ meats, connective tissue, and bone marrow (essentially nose-to-tail of an animal), as well as some fermented plant foods.

The Plant-Based Backlash

When you listen to the rhetoric of some of the carnivore movement’s most enthusiastic proponents, you might get the idea that, in addition to any health benefit or scientific claim, there’s also a significant element of backlash to plant-based diets.

Traditionally, meat-eating has been associated with masculinity and machismo (although films like The Game Changers are starting to challenge that association), so the rise of plant-based eating has triggered a “culture war” response that goes far beyond nutrition. There’s a lot of name-calling and invitations to settle differences through MMA cage matches, for example.

I haven’t personally been invited into the octagon by a carnivore enthusiast to duke it out, but I do have a number of friends who adopted a carnivore diet approach and initially experienced some of the promised benefits. Their inflammation lessened, and most lost weight — at first.

None of them stuck with it long-term, because they found it — and I’m quoting them all here — “gross.” But still, their stories left me with questions. How could they possibly benefit, even for a short time, from a diet so diametrically opposed to the plant-based diet that most science shows is the healthiest for humans? Isn’t too much meat bad for everything from heart disease to type 2 diabetes to obesity?

Let’s dive in to explore the health claims of carnivore diets, and what the research really says about eating this way.

Health Claims of Carnivore Diets

Carnivore advocates claim a broad array of health benefits. I don’t have the space here to examine every single claim, so I’ll focus on the most common ones: weight loss, brain health, reduced inflammation and remission of autoimmune disease, and improved digestion.

Spoiler alert: The scientific evidence supporting these claims is — and I’m being extremely charitable here — limited and inconclusive. There are no long-term, large-scale clinical trials that specifically examine the effects of carnivore diets on any of these aspects of health. Instead, there are a lot of anecdotes, a few online surveys, and small studies of limited scope and duration.

Carnivore Diets and Weight Loss

Currently, no studies have been conducted that looked at weight loss with carnivore diets. However, the theory that low-carb diets are supposed to lead to weight loss is known as the Carbohydrate-Insulin Model (CIM) of obesity.

Proponents assert that eating carbs triggers a release of insulin, which, according to this model, leads to hunger and overeating, and ultimately, fat storage and excess weight.

One study did show that low-carb diets high in animal foods can lead to weight loss. But, the diet did include some plant foods. The bigger issue, though, was its severe calorie restriction. The study’s average low-carb dieter took in fewer than 1,500 calories per day — an amount that all but guarantees weight loss in most people, regardless of the foods consumed.

A clinical trial published in the prestigious journal Nature Medicine in 2021 tested a low-fat, minimally processed, plant-based diet against a low-carb, minimally processed, animal-based diet.

Participants could eat as much of their assigned diet as they wanted — no limits other than personal preference and satiety. And the results directly contradicted the predictions of the Carbohydrate-Insulin Model. Those eating the low-fat diet consumed almost 700 fewer calories per day than the low-carb eaters. “Despite the large differences in calorie intake,” the researchers reported that “participants (expressed) no differences in hunger, enjoyment of meals, or fullness between the two diets. Participants lost weight on both diets, but only the low-fat diet led to a significant loss of body fat.”

Indeed, other studies have shown that the most weight-loss-friendly foods are, in fact, plants. A study published in the British Journal of Nutrition even concluded that each additional year of adopting a vegan diet decreases the risk of obesity by 7%.

Meanwhile, increased fat intake and high-fat diets (looking at you here, carnivore diets) actually have a strong association with increased body weight and risk of overweight and obesity.

Carnivore Diet and Brain Health

Proponents of carnivore diets often describe better cognitive function and improved mental clarity. But, as of this writing, no scientific studies have been conducted to investigate these claims.

The only evidence I could find was a survey of people who belonged to carnivore groups on social media. Of course, a survey is inherently lacking objectivity in some pretty big ways. For one thing, only people who had been on the diet for at least six months were invited to take the survey. It stands to reason that if someone had a worsening of symptoms after, say, two months — they would probably stop the diet. And, for another, the group of people “surveyed” were themselves members of identity groups that subscribe to the ideology of the diet enough to belong to a group of fellow adherents.

This seems kind of like asking a group of fish if they enjoy swimming; you’re unlikely to get an unbiased opinion.

Nevertheless, in the context of this less-than-objective methodology, many of the survey respondents reported high levels of satisfaction and improvements in overall health and well-being, including cognitive and psychiatric symptoms, which they attributed to their diet.

There are many possible reasons for these alleged improvements. Of course, the carnivore diet could have been helpful, at least in the short run, for this particular collection of people. Or it may be a case of the placebo effect, which can, at least in the short run, lead to dramatic benefits for a great many people.

But mental gains can also be plausibly explained by what carnivore dieters have eliminated: substances like alcohol, refined sugars, and processed foods. It’s not hard to imagine many people feeling better after giving those up.

Diet is one of the key lifestyle factors that can be modified to significantly reduce the risk of developing Alzheimer’s disease. But it’s plant-based diets that contain key nutrients like polyphenols and fiber that protect against the insulin resistance that can lead to Alzheimer’s.

There’s also solid evidence that plant-based foods can boost mood. Plus, the more saturated fat (remember that for most people the vast majority of the saturated fat in their diet comes from animal products) that people consume, the higher their risk of developing neurodegenerative disorders. Mono- and polyunsaturated plant fats, on the other hand, reduce that risk.

If there’s one food that you can think of as a brain superfood, it’s actually leafy greens — although greens are not allowed on a strict carnivore diet. However, in one study, those who ate the most greens were the proud owners of brains that were functionally 11 years younger than those who ate the fewest.

Other brain protectors include berries — eating blueberries and strawberries delayed cognitive decline by two and a half years in one study. Some interpretations of the carnivore diets do allow fruit — ostensibly because plants “want” us to eat their fruit to spread their seeds.

Carnivore Diets, Inflammation, and Autoimmune Conditions

In the same somewhat dubious survey discussed above, some respondents wrote that adopting a carnivore diet led to improvements in various inflammatory conditions. Out of hundreds of survey respondents with prior autoimmune conditions, 10% claimed complete resolution, and another 14% reported improvement.

Mikhaila Peterson also claims she healed her autoimmune issues through the “Lion Diet” and referenced those survey results in her TEDx talk as corroborating evidence. (TEDx refused to publish her talk, explaining that it failed to adhere to their content guidelines and lacked nuance, offering a purely anecdotal experience and no actual scientific evidence.)

A core mechanism of autoimmune disease is a malfunctioning immune system. While we don’t yet understand the causes and initial triggers of many autoimmune conditions, we know that lifestyle choices, particularly related to food, can play a key role in managing and, in some cases, even reversing many of these diseases.

But it’s plant-based diets that have been proven to help with inflammation and autoimmune disease. Meat and high-fat, animal protein-rich diets on the other hand, especially red meat, have consistently been associated with more inflammation.

So how do we reconcile the science with the experience of Mikhaila Peterson and other carnivore diet adherents? It’s possible that a body in an inflamed state could find certain compounds in plants triggering, and that, in some cases, taking a break could provide relief.

But this is not a great long-term solution. Rather than live in a metaphorical “food bubble” in which nothing challenges the chronically inflamed body, the goal should be to bring down inflammation so that eating plants — which offer myriad powerful health benefits — doesn’t cause symptoms. Traditional elimination diets can allow for a more methodical and less draconian approach.

Carnivore Diets and Digestion

A study that is objectively even less rigorous than the social media study already mentioned asked a couple hundred carnivore dieters about their “beliefs and experiences.” Here as well, dieters claimed improvements in inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), and Crohn’s disease.

But again, the vast majority of objective research points to carnivorous dietary patterns contributing to a greater likelihood of IBD, not remission from it.

Advocates of carnivore diets claim that plant foods are high in toxins and harmful compounds like antinutrients, those nasty compounds plants produce to discourage us from eating them.

And it’s true that when isolated from the foods that contain them, antinutrients may lead to some unwanted effects. But when consumed as part of a varied whole foods diet, they participate in diverse and complex interactions with vitamins, minerals, and the gut microbiome, and can actually contribute to significant health benefits.

Another explanation for why some people experience improved digestion during the initial phase of a carnivore diet is the complete absence of fiber. However, if someone was already consuming low amounts of fiber — and only 6% of the US population gets the recommended amount — they likely lacked the microbial diversity required to adequately digest that fiber.

Fiber increases microbial diversity and gut health; studies show those consuming the most fermented and fiber-rich plant foods had a more diverse gut microbiome — and a stronger immune system, with decreased inflammatory markers — compared to those who consumed less.

Meat, of course, contains zero fiber, and therefore a meat-only diet is not a recipe for long-term health. On the contrary, one meta-analysis study found every 10 grams of fiber consumed per day cuts mortality risk by 10%.

Carnivore Diet Risks and Side Effects

We’ve looked at the purported benefits of carnivore diets. But what about the risks? Is there the possibility of unwanted and serious side effects?

In fact, there are many anecdotal reports of unpleasant and sometimes dangerous side effects with extremely low-carb or zero-carb diets. These include diarrhea, constipation, weight gain, muscle cramps, hair loss or thinning, insomnia, dry skin, itchiness, heart rate changes, brittle fingernails, and menstrual irregularity.

Bowel irregularity, whether diarrhea or constipation, is typically caused by a lack of dietary fiber. But many of the other symptoms are attributable to nutritional deficiencies and imbalances that can occur in any extreme diet that lacks diversity. The carnivore diet, in particular, is missing not just fiber but also antioxidants, polyphenols, vitamins, minerals, probiotics, and prebiotics — all of which are essential for good health.

Without vitamin C from fruits, vegetables, or supplements, carnivore dieters are actually at risk for scurvy, putting them in the company of 17th-century British sailors. And vitamin C and other antioxidants are important for combating free radicals in the body. How serious is that? The buildup of free radicals, or “oxidative stress,” is a leading cause of deterioration and disease, including memory loss, autoimmune disease, heart disease, type 2 diabetes, and cancer.

Most dietitians, even those who don’t advocate for plant-based diets, consider carnivore diets dangerous for humans. Animal protein is associated with heart disease and poor markers of metabolic health such as type 2 diabetes, insulin resistance, and nonalcoholic fatty liver disease. Red and processed meats are considered carcinogenic, with particular contributions to colorectal cancer. And as we saw earlier, high animal product consumption is also associated with Alzheimer’s, inflammation, and autoimmune diseases.

Meat also promotes the growth of unfavorable bacteria that leads to the production of TMAO, which inflames the endothelium (the inner lining of blood vessels) and further promotes heart disease.

And high-meat diets can deliver worrisome quantities of heme iron, which has prooxidant effects that promote cardiovascular disease.

Eating plant foods, on the other hand, has consistently contributed to a reduction in chronic diseases like heart disease and cancer while promoting longevity.

All in all, relying almost solely on animal-derived foods goes against most medical and nutrition advice which is that eating more whole plant foods and less meat, eggs, and dairy is actually the healthiest way to eat.

Carnivore Diets’ Environmental Impacts

When we evaluate the health of a diet, it makes sense to look at how it impacts not just the individuals following it, but the planet as a whole. And eating mostly meat has serious implications for the environment.

Adopting a meat-free, and especially beef-free, diet is one of the most powerful things an individual can do to help fight climate change. That’s because animal agriculture is like a protein factory in reverse, cycling amino acids through animals instead of sourcing them directly from plants.

Shifting from animal to plant foods can also significantly decrease the amount of land required for agriculture, which in turn can lower greenhouse gas emissions.

Animal agriculture is a leading cause of deforestation, especially in the Amazon rainforest — one of the most biodiverse regions in the world. Forests are being cut down not just to provide grazing land for cattle, but also to create fields to grow crops that get turned into animal feed. And grass-fed meat is not much better either, as it can use even more land per pound of food produced.

Additionally, most cattle feed in the industrialized world is bioengineered (aka GMO), which contributes to a number of environmental and health problems globally.

At the risk of stating the obvious, eating nothing but animal products is not great for the animals either. More demand for meat means more animals slaughtered to meet that demand. And the overwhelming majority of that meat is produced in factory farms.

Animals so confined are given huge quantities of antibiotics to fatten them up and to keep them alive — drugs that are contributing to the alarming rise in antibiotic-resistant superbugs.

In short, what’s bad for the animals also ends up being bad for us.

Carnivore Diets Are Not Healthy — for People or the Planet

The carnivore diet’s alleged benefits have sparked fierce debate in the wellness world. But the scientific basis for these claims remains limited and inconclusive at best. While some individuals report success alleviating autoimmune conditions and experiencing weight loss through total elimination of carbohydrates, and of course I wish these people nothing but the best of health, there has so far not been a single comprehensive study suggesting that the results are replicable or sustainable.

Given what we do know about nutrition, it seems likely that you can achieve similar or better results using moderate caloric restriction, or with an elimination diet. And both of these methods are likely going to be far more healthful than eating nothing but meat and other animal products.

There are also concerns about potential nutritional deficiencies, chronic disease impact, and environmental ethics of meat-centric diets. From a global perspective, these diets magnify the environmental harms associated with meat production. And by eliminating plant foods, carnivore diet followers are missing out on powerful dietary compounds proven to increase longevity and improve health outcomes.

As researchers continue to investigate the impact of diet on our well-being, it’s evident that incorporating a wide array of nutrient sources, not limiting them, holds the key to promoting both individual health and global sustainability.

Tell us in the comments:

• Do you know anyone who’s adopted a carnivore diet?
• What do you think of the carnivore diet?
• How much do environmental concerns influence what you eat?

Featured Image: iStock.com/Luke Chan

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• What’s All Wrong About Annals Of Internal Medicine’s Red and Processed Meat Advice

The post The Carnivore Diet: What the Research Really Says About its Impact on People and the Planet appeared first on Food Revolution Network.